In and Outpatients Bacteria Antibiotic Resistances in Positive Urine Cultures from a Tertiary Care Hospital in the Western Part of Romania-A Cross-Sectional Study.

BACKGROUND/OBJECTIVES: Urinary tract infections (UTI) represent a global problem with implications for mortality and morbidity. Published data present different bacterial incidences and different antibiotic resistance. The objective of our study is to evaluate the bacteria distribution in positive urine cultures in a mixed adult population and evaluate the differences in antibiotic resistance in in- and outpatients.

METHODS

We analyzed 1186 positive urine cultures in 2021 from the Emergency County Hospital "Pius Brinzeu" from Timisoara, Romania. We evaluated the bacteria distribution and antibiotic resistance stratified by in and outpatients from a mixed adult population.

RESULTS

The median age was 67, with 65.7% females and 28.5% were outpatients. In inpatients, the most commonly identified bacteria was , followed by spp., and spp., while in outpatients, , spp., and spp. were the leading ones. Overall, presented the highest resistance rate to ampicillin, spp. to ciprofloxacin, spp. to cephalosporins, and spp. to trimethoprim/sulfamethoxazole. Inpatients presented higher resistance rates for to ceftazidime, cefuroxime, gentamycin, ciprofloxacin, and trimethoprim/sulfamethoxazole, spp. to most cephalosporin, gentamycin and levofloxacin, spp. to gentamycin and spp. to gentamycin and quinolones when compared to outpatients. The highest incidence of extensively drug-resistant (XDR) bacteria was among , followed by spp., and spp.

CONCLUSIONS

susceptibility. Bacteria identified in inpatients' positive urine cultures present higher resistance rates to several antibiotics. Our study could be a foundation for a local or even national guideline for the antibiotic treatment of urinary tract infections.