国际病毒分类委员会病毒分类概况：2025年。

ICTV Virus Taxonomy Profile: 2025.

作者信息

Krupovic Mart, Wang Fengbin, Cvirkaite-Krupovic Virginija, Kuhn Jens H, Dolja Valerian V, Prangishvili David, Egelman Edward H, Koonin Eugene V

机构信息

Institut Pasteur, Université Paris Cité, CNRS UMR6047, Archaeal Virology Unit, 75015 Paris, France.

Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35233, USA.

出版信息

J Gen Virol. 2025 Mar;106(3). doi: 10.1099/jgv.0.002091.

DOI:10.1099/jgv.0.002091

PMID:40138208

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12282232/

Abstract

Viruses assigned to the realm have linear, dsDNA genomes in which the DNA is structured in the A-form rather than the usual B-form. Virions are flexible or rigid filaments, with or without envelopes. Adnavirians share homologous major capsid proteins (MCPs) with a distinct -helical structural fold not observed in other known viruses. The MCPs form homodimeric or heterodimeric capsomers that wrap around and condense the genomic dsDNA into helically symmetrical virions. Adnavirians infect hyperthermophilic, thermoacidophilic and methanotrophic archaea. This is a summary of the International Committee on Taxonomy of Viruses Report on the realm , which is available at ictv.global/report/adnaviria.

摘要

归入该域的病毒具有线性双链DNA基因组，其中DNA呈A构象而非常见的B构象。病毒粒子为柔性或刚性丝状，有包膜或无包膜。腺病毒与其他已知病毒中未观察到的具有独特α螺旋结构折叠的主要衣壳蛋白（MCP）具有同源性。MCP形成同二聚体或异二聚体壳粒，围绕基因组双链DNA并将其浓缩成螺旋对称的病毒粒子。腺病毒感染嗜热、嗜热嗜酸和甲烷营养古菌。这是国际病毒分类委员会关于该域的报告摘要，可在ictv.global/report/adnaviria获取。