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薰衣草口服滴剂对减轻根管治疗患者牙科焦虑的影响:一项随机临床试验。

Effect of Lavender Oral Drops in Reducing Dental Anxiety Among Patients Requiring Endodontic Treatment: A Randomised Clinical Trial.

作者信息

Razavian Hamid, Mazaheri Mohammad, Shiri Amirhossein

机构信息

Department of Endodontics, Dental Materials Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

Department of Persian Medicine, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Eur Endod J. 2025 Jan;10(1):66-72. doi: 10.14744/eej.2024.06641.

Abstract

OBJECTIVE

Patients requiring endodontic treatment often experience high levels of anxiety. The aim of this research is to investigate the effect of oral administration of lavender on the anxiety score of these patients.

METHODS

In this double-blinded randomized clinical trial conducted in 2021, 64 patients with symptomatic irreversible pulpitis were recruited using a simple random sampling technique. Blinding was achieved for both the patients and the evaluators. The samples were split into intervention and control groups using a table of random integers to randomize them. An hour before the commencement of the procedure, the patients filled out the dental anxiety questionnaire. Twenty drops of water in 250 ml of water were given to the control group, whereas 20 drops of lavender extract added to 250 ml of water were given to the intervention group. Two groups completed the anxiety questionnaire 60 minutes after ingesting the remedies. To analyse the data, paired and independent t-tests, and multiple regression analysis were used.

RESULTS

64 patients were randomized and analyzed. Thirty-two of them who were in the control group experienced a substantially smaller decrease in their dental anxiety score compared to those 32 patients who were in the control group (p=0.001). This difference persisted even after grouping individuals by age, sex, and weight.

CONCLUSION

The administration of oral lavender extract drops to individuals requiring endodontic treatment appeared to significantly reduce their dental anxiety scores. The research registration number in the Iranian Registry of Clinical Trials is IRCT20120908010773N2, which is available at https: //irct.behdasht.gov.ir/. (EEJ-2024-03-50).

摘要

目的

需要进行牙髓治疗的患者常常会经历高度焦虑。本研究的目的是调查口服薰衣草对这些患者焦虑评分的影响。

方法

在这项于2021年进行的双盲随机临床试验中,采用简单随机抽样技术招募了64例有症状的不可逆性牙髓炎患者。患者和评估者均实现了盲法。使用随机整数表将样本随机分为干预组和对照组。在治疗开始前一小时,患者填写牙科焦虑问卷。对照组给予250毫升水中滴入20滴水,而干预组给予250毫升水中加入20滴薰衣草提取物。两组在摄入药物60分钟后完成焦虑问卷。为分析数据,使用了配对和独立t检验以及多元回归分析。

结果

64例患者被随机分组并进行分析。与对照组的32例患者相比,干预组的32例患者的牙科焦虑评分下降幅度明显更小(p=0.001)。即使按年龄、性别和体重对个体进行分组后,这种差异仍然存在。

结论

对需要进行牙髓治疗的个体给予口服薰衣草提取物滴剂似乎能显著降低他们的牙科焦虑评分。该研究在伊朗临床试验注册中心的注册号为IRCT20120908010773N2,可在https://irct.behdasht.gov.ir/获取。(EEJ - 已发表文章编号 - 2024 - 03 - 50) 。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ac/11971705/9522910fae7a/EEJ-10-066-g001.jpg

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