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牙槽骨炎的管理:2型糖尿病患者的新型再生技术

Management of alveolar osteitis: new regenerative techniques in patients with type 2 diabetes.

作者信息

Khachatryan Hakob, Hovhannisyan Margarita, Hakobyan Gagik

机构信息

Department of Oral and Maxillofacial Surgery, Yerevan State Medical University, after M. Heratsi, Maxillofacial Surgeon, Central Clinical Military Hospital (Ministry of Defence of The Republic of Armenia), Yerevan, Armenia.

Department of Military Surgery, Yerevan State Medical University after M. Heratsi, Yerevan, Armenia.

出版信息

Oral Maxillofac Surg. 2025 Apr 8;29(1):77. doi: 10.1007/s10006-025-01375-x.

Abstract

OBJECTIVES

Evaluation of the effectiveness Gengigel Oral Gel (hyaluronic acid ) and photobiomodulation (magnetic laser) in the treatment of alveolar osteitis in patients with type 2 diabetes mellitus.

METHODS

This is a blind RCT study clinical prospective study in 69 patients with type 2 diabetes mellitus with alveolar osteitis. The subjects selected for study were examined under the inclusion and exclusion criteria and sign the written consent. The patients were blind randomly assigned into two groups: The Group I included 35 patients with alveolar osteitis, in which complex treatment including HA and magnetic laser therapy was carried out. The Group II is represented by 34 patients, with alveolar osteitis received treatment including antiseptic and inflammatory agents. Healing time and pain levels of the alveolar socket of the extracted tooth were appreciated. The pain levels in dynamics were assessed according to VAS.

RESULTS

After the 5th treatment session, 91% of patients in the 1st group had a VAS score of 0 (no pain), whereas in 9% of patients, the VAS score was 1-3. In group 2, a similar result of the VAS score was recorded but only on the 8th day of treatment.

CONCLUSION

The results show that the use of Gengigel Oral Gel (hyaluronic acid ) and photobiomodulation(magnetic laser) recommended for the treatment of dry socket in patients with type 2 diabetes mellitus, can be considered as a promising method, as it has not only anti-inflammatory but also pronounced analgesic and tissue regenerating properties.

CLINICAL TRIAL NUMBER

Not applicable.

摘要

目的

评估庚基吉尔口腔凝胶(透明质酸)和光生物调节(磁激光)在治疗2型糖尿病患者牙槽骨炎中的有效性。

方法

这是一项针对69例患有牙槽骨炎的2型糖尿病患者的盲法随机对照临床试验前瞻性研究。入选研究的受试者在纳入和排除标准下接受检查并签署书面同意书。患者被随机分为两组:第一组包括35例牙槽骨炎患者,采用包括透明质酸和磁激光治疗的综合治疗。第二组由34例牙槽骨炎患者组成,接受包括防腐剂和抗炎药的治疗。评估拔牙后牙槽窝的愈合时间和疼痛程度。根据视觉模拟评分法(VAS)评估动态疼痛程度。

结果

在第5次治疗后,第一组91%的患者VAS评分为0(无疼痛),而9%的患者VAS评分为1 - 3。在第二组中,仅在治疗第8天记录到类似的VAS评分结果。

结论

结果表明,使用庚基吉尔口腔凝胶(透明质酸)和光生物调节(磁激光)治疗2型糖尿病患者的干槽症,可被视为一种有前景的方法,因为它不仅具有抗炎作用,还具有显著的镇痛和组织再生特性。

临床试验编号

不适用。

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