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三维气管支气管重建术用于规划恶性上气道狭窄的内镜支架置入术。

Three-dimensional tracheo-bronchial reconstruction to plan endoscopic stent insertion for malignant upper airway stenosis.

作者信息

Leonardi Beatrice, Forte Stefano, Marella Antonio, Panini D'Alba Francesco, Vicario Giuseppe, Bergameo Grazia, Capasso Francesca, Leone Francesco, Giorgiano Noemi Maria, Pica Davide Gerardo, Martorana Emanuele, Villa Riccardo, Marvulli Maria, Monti Riccardo, Messina Gaetana, Ferrigno Francesco, Mosella Marco, Chiodini Paolo, Vicidomini Giovanni, Fiorelli Alfonso

机构信息

Thoracic Surgery Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.

Genomics and Molecular Oncology Unit, Istituto Oncologico Mediterraneo, Viagrande, Italy.

出版信息

Interdiscip Cardiovasc Thorac Surg. 2025 Mar 29;40(4). doi: 10.1093/icvts/ivaf095.

Abstract

OBJECTIVES

Malignant central airway obstruction (MCAO) is a condition characterized by severe dyspnoea and high mortality. Tracheo-bronchial stents have emerged as an effective treatment to restore airway patency. Our study aimed to evaluate the efficacy of 3D reconstruction of the upper airways to plan tracheo-bronchial stent insertion for MCAO.

METHODS

This was a retrospective, single-centre observational study. We analysed data of patients undergoing tracheo-bronchial stent insertion for MCAO from January 2012 to January /2024. Patients undergoing tracheo-bronchial stent insertion for MCAO with 3D reconstruction (3D Reconstruction Group) were compared with patients treated prior to the use of 3D reconstruction (Standard Group).

RESULTS

A total of 136 patients were included in our study: 40 patients (29%) in the 3D Reconstruction Group and 96 patients (71%) in the Standard Group. Restore of airway patency was obtained in 96% of patients, without differences between groups (P = 0.48). Median operative time was 40 min in 3D Reconstruction Group vs 48 min in Standard Group, with a percentage reduction of 17% in the 3D Group (P = 0.03). Stent migration was less frequent in 3D Reconstruction Group than in Standard Group, being 5% vs 17% (P = 0.04). There were no significant differences in 30- and 90-day mortality.

CONCLUSIONS

Three-dimensional reconstruction of the upper airways was associated with reduced operative time and stent migration rate in patients with MCAO. Reconstructing patients' anatomical features optimizes the procedure without any added cost or delay of the treatment.

摘要

目的

恶性中央气道阻塞(MCAO)是一种以严重呼吸困难和高死亡率为特征的疾病。气管支气管支架已成为恢复气道通畅的有效治疗方法。我们的研究旨在评估上气道三维重建在规划MCAO气管支气管支架置入术中的疗效。

方法

这是一项回顾性单中心观察性研究。我们分析了2012年1月至2024年1月期间因MCAO接受气管支气管支架置入术的患者数据。将接受MCAO气管支气管支架置入术并进行三维重建的患者(三维重建组)与在使用三维重建之前接受治疗的患者(标准组)进行比较。

结果

我们的研究共纳入136例患者:三维重建组40例(29%),标准组96例(71%)。96%的患者气道通畅得以恢复,两组之间无差异(P = 0.48)。三维重建组的中位手术时间为40分钟,标准组为48分钟,三维组减少了17%(P = 0.03)。三维重建组的支架移位发生率低于标准组,分别为5%和17%(P = 0.04)。30天和90天死亡率无显著差异。

结论

上气道三维重建与MCAO患者手术时间缩短和支架移位率降低相关。重建患者的解剖特征可优化手术过程,且不会增加任何成本或延误治疗。

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