Chan Sandra S M, Wong Oscar W H, Hussain Samara, Tsoi Kelvin K F, Ma Karen K Y, Chau Steven W H, Ma Suk Ling, Lai Kelly Y C, Chu Winnie C W, Lo Holly H L, Ho Stephy W S, Leung Ching Chi, Yiu Karen K L, So Suzanne H W, Sham Pak C, Hung Se Fong, Leung Patrick W L
Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
Lancet Reg Health West Pac. 2025 Mar 29;57:101533. doi: 10.1016/j.lanwpc.2025.101533. eCollection 2025 Apr.
Childhood and adolescence, as critically important developmental stages, set the premise for the lifelong trajectory of health and well-being. Epidemiologic evidence abounds in purporting that half of all lifetime mental disorders begin in adolescence. Epidemiologic data based on structured clinical diagnostic assessments are disproportionately scarce in Asian countries that host fast-growing youth population along a wide socioeconomic spectrum in the course of globalisation.
A cross-sectional school-based epidemiologic survey was conducted on a representative random sample of children and adolescents aged 6-17 years from September 2019 to June 2023 in Hong Kong Special Administrative Region (Hong Kong SAR). The main diagnostic measures were 31 DSM-5 disorders assessed with Diagnostic Interview Schedule for Children, Version 5 (DISC-5) on the whole study sample. One parent/caregiver of each participant was interviewed for cases from primary schools. Separate parent/caregiver and student interviews were conducted for cases from secondary schools where research diagnoses derived from both sources in the adolescent/caregiver pair were combined at disorder level. A host of developmental and psychosocial factors were also collected. The study sample was reconstituted according to the discrepancy between the study population and official population data (census mid-year 2022 and Education Bureau) in terms of age, sex, ethnicity, household income and school type to give weight-adjusted prevalence estimation of various disorders.
The final weighted sample consisted of 6082 participants. The 12-month prevalence of having only one DSM-5 disorder was 13.5% (95% CI: 12.6-14.3%), while the 12-month prevalence of having two or more DSM-5 disorders was 11.0% (95% CI: 10.2-11.8%). The most prevalent disorders/categories of disorders were attention-deficit/hyperactivity disorder (ADHD) (10.2%, 95% CI: 9.4-11.0%); any disruptive, impulse control and conduct disorders (8.8%, CI:8.1-9.5%); any anxiety disorders (6.1%, 95% CI: 5.5-6.7%); any depressive disorders (5.4%, 95% CI: 4.8-6.0%). The 12-month prevalence rates of suicide ideation, plan, and attempt (not including the non-suicidal self-injury) were respectively 3.9% (95% CI: 3.4-4.4%), 1.9% (95% CI: 1.6-2.3%), 1.1% (95% CI: 0.8-1.3%). Parental anxiety and depressive symptoms, any clinically significant sleep disorder, and major school maladjustments (such as repeating a grade, school suspension, absenteeism) were significant factors associated positively (ORs: 1.1-3.37, p-values < 0.01-0.001) with ADHD, externalizing and internalizing disorders in multivariate logistic regressions that account for a multitude of developmental and environmental factors.
This study provides the first comprehensive mental health survey on children and adolescents that might inform other high-income regions in Asia and other robustly thriving economies in the coming decades. The common mental health problems present unmet needs in the school community and yet the related factors are accessible and potentially modifiable. Sustainable mental health initiatives should prioritise an integrated approach to the well-being of parent-child dyad, early detection and intervention targeting sleep disorders, and build a holistic learning support environment in school communities.
Health and Medical Research Fund, Health Bureau, Hong Kong Special Administrative Region (MHS-P1(Part 1)-CUHK).
童年和青少年时期是至关重要的发育阶段,为一生的健康和幸福轨迹奠定了基础。流行病学证据充分表明,所有终生精神障碍中有一半始于青春期。在全球化进程中,亚洲国家拥有快速增长的青年人口,涵盖广泛的社会经济阶层,但基于结构化临床诊断评估的流行病学数据却极为匮乏。
2019年9月至2023年6月,在香港特别行政区(香港特区)对6至17岁儿童和青少年的代表性随机样本进行了一项基于学校的横断面流行病学调查。主要诊断措施是使用儿童诊断访谈量表第5版(DISC-5)对整个研究样本评估31种DSM-5障碍。对小学的每个参与者的一位家长/照顾者进行访谈。对中学的病例分别进行家长/照顾者和学生访谈,其中青少年/照顾者对中来自两个来源的研究诊断在障碍层面进行合并。还收集了一系列发育和心理社会因素。根据研究人群与官方人口数据(2022年年中人口普查和教育局)在年龄、性别、种族、家庭收入和学校类型方面的差异对研究样本进行重新构建,以给出各种障碍的加权患病率估计。
最终加权样本包括6082名参与者。仅有一种DSM-5障碍的12个月患病率为13.5%(95%置信区间:12.6 - 14.3%),而有两种或更多DSM-5障碍的12个月患病率为11.0%(95%置信区间:10.2 - 11.8%)。最常见的障碍/障碍类别是注意力缺陷/多动障碍(ADHD)(10.2%,95%置信区间:9.4 - 11.0%);任何破坏性行为、冲动控制和品行障碍(8.8%,置信区间:8.1 - 9.5%);任何焦虑障碍(6.1%,95%置信区间:5.5 - 6.7%);任何抑郁障碍(5.4%,95%置信区间:4.8 - 6.0%)。自杀意念、计划和企图(不包括非自杀性自伤)的12个月患病率分别为3.9%(95%置信区间:3.4 - 4.4%)、1.9%(95%置信区间:1.6 - 2.3%)、1.1%(95%置信区间:0.8 - 1.3%)。在考虑了多种发育和环境因素的多变量逻辑回归中,父母的焦虑和抑郁症状、任何具有临床意义的睡眠障碍以及主要的学校适应不良(如留级、停学、旷课)是与ADHD、外化和内化障碍呈正相关的显著因素(比值比:1.1 - 3.37,p值 < 0.01 - 0.001)。
本研究提供了第一项关于儿童和青少年的全面心理健康调查,可能会为未来几十年亚洲的其他高收入地区以及其他蓬勃发展的经济体提供参考。常见的心理健康问题在学校社区中存在未满足的需求,但相关因素是可及且可能可改变的。可持续的心理健康倡议应优先采用综合方法促进亲子二元组的幸福,针对睡眠障碍进行早期检测和干预,并在学校社区建立全面的学习支持环境。
香港特别行政区卫生署健康及医学研究基金(MHS-P1(Part 1)-CUHK)