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科罗拉多州丹佛市注射吸毒者皮肤脓肿的患病率及危险因素

Cutaneous Abscess Prevalence and Risk Factors Among People Who Inject Drugs in Denver, Colorado.

作者信息

Olson Nicholas L, Al-Tayyib Alia, Rowan Sarah E

机构信息

University of Colorado School of Medicine, Aurora, Colorado, USA.

Public Health Institute, Denver Health, Denver, Colorado, USA.

出版信息

Open Forum Infect Dis. 2025 Mar 18;12(4):ofaf165. doi: 10.1093/ofid/ofaf165. eCollection 2025 Apr.

Abstract

BACKGROUND

Skin and soft tissue infections (SSTIs) are considered common problems for people who inject drugs (PWID), yet few studies actually quantify injection-related SSTIs or identify contributing risk behaviors. We report the prevalence of self-reported cutaneous abscesses among PWID and explore associations between abscesses and injection-related behaviors.

METHODS

PWID were recruited to participate in the National HIV Behavioral Surveillance system in Denver, Colorado, and answered questions about their experiences with abscesses and injection-related activities. We used χ statistics to assess differences between sociodemographic and healthcare characteristics and injection-related behaviors associated with self-reported abscess in the past 12 months. We used generalized linear models to estimate the unadjusted and adjusted prevalence ratios to describe the association between using sterile needles and abscess in the past 12 months. We also examined the association between using alcohol swabs and abscess in the past 12 months.

RESULTS

Of the 533 participants who completed the survey in 2018, 257 (48%) reported having at least 1 abscess in the past 12 months while 98 of the 277 (35%) participants in 2022 reported an abscess. In both 2018 and 2022, participants who reported less consistent use of sterile needles were significantly more likely to report having an abscess in the past 12 months.

CONCLUSIONS

These findings highlight the relatively high prevalence of recent abscesses among PWID and underscore the need to identify simple, accessible prevention strategies for use in clinical and nonclinical settings.

摘要

背景

皮肤和软组织感染(SSTIs)被认为是注射吸毒者(PWID)的常见问题,但实际上很少有研究对与注射相关的SSTIs进行量化或确定相关的风险行为。我们报告了PWID中自我报告的皮肤脓肿患病率,并探讨了脓肿与注射相关行为之间的关联。

方法

招募PWID参与科罗拉多州丹佛市的国家艾滋病行为监测系统,并回答有关他们脓肿经历和注射相关活动的问题。我们使用χ统计量来评估社会人口统计学和医疗保健特征以及过去12个月内与自我报告脓肿相关的注射相关行为之间的差异。我们使用广义线性模型来估计未调整和调整后的患病率比值,以描述过去12个月内使用无菌针头与脓肿之间的关联。我们还研究了过去12个月内使用酒精棉签与脓肿之间的关联。

结果

在2018年完成调查的533名参与者中,257人(48%)报告在过去12个月内至少有1次脓肿,而2022年277名参与者中有98人(35%)报告有脓肿。在2018年和2022年,报告使用无菌针头不太一致的参与者在过去12个月内报告有脓肿的可能性显著更高。

结论

这些发现突出了PWID近期脓肿的相对高患病率,并强调需要确定简单、可及的预防策略,用于临床和非临床环境。

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本文引用的文献

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[Unsafe practices fostering cutaneous abscesses in people who inject substances : Results from the ANRS-OUTSIDER study].
Rev Epidemiol Sante Publique. 2023 Oct;71(5):102142. doi: 10.1016/j.respe.2023.102142. Epub 2023 Aug 23.
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HIV Injection Risk Behaviors among HIV-Negative People Who Inject Drugs Experiencing Homelessness, 23 U.S. Cities.
J Soc Distress Homeless. 2020 Mar 6;1(9). doi: 10.1080/10530789.2021.1892931.
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A community-based study of abscess self-treatment and barriers to medical care among people who inject drugs in the United States.
Health Soc Care Community. 2022 Sep;30(5):1798-1808. doi: 10.1111/hsc.13559. Epub 2021 Sep 1.
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Recurring Severe Injection-Related Infections in People Who Inject Drugs and the Need for Safe Injection Sites in Madrid, Spain.
Open Forum Infect Dis. 2021 May 25;8(7):ofab251. doi: 10.1093/ofid/ofab251. eCollection 2021 Jul.
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