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乳腺癌国际组织成员间的气候变化影响与可持续性整合

Climate change impacts and sustainability integration among breast international group members.

作者信息

O'Reilly Seamus, Griffiths Jessica, Fox Lisa, Weadick Catherine S, My Oo Nay, Murphy Lucy, O'Leary Robert, Goulioti Theodora, Adam Virginie, Razis Evangelia D, Lindholm Barbro, Werustsky Gustavo, Cameron David, Bliss Judith

机构信息

Department of Medical Oncology, Cork University Hospital, Wilton, Cork, Ireland; Cancer Trials Ireland, Royal College of Surgeons, St Stephens Green, Dublin, Ireland; Cancer Research @UCC, College of Medicine and Health, University College Cork, Cork, Ireland.

Clinical Trials and Statistics Unit, Institute of Cancer Research, London, United Kingdom.

出版信息

Breast. 2025 Jun;81:104469. doi: 10.1016/j.breast.2025.104469. Epub 2025 Apr 10.

Abstract

BACKGROUND

Integration of sustainability measures into clinical research would translate into less healthcare related climate impacts.

METHODS

We assessed climate change impacts, existing sustainability engagement, and challenges and facilitators to climate change mitigation strategies among Breast International Group (BIG) members. A 30 item web based survey assessing climate impacts, sustainability engagement, challenges to and facilitators of engagement, and sustainability integration in funding applications was developed, and circulated electronically between November 2023 and March 2024.

RESULTS

Thirty four members (research groups and data centres) and participating sites across 5 continents, and BIG headquarters responded. Twenty six responses were received from 21 organisations, 20 from 17 participating sites. No responses were obtained from 28 groups. Trial conduct at a third of member groups had been impacted by climate change impacts such as destroyed infrastructure. 78 % of groups agreed that sustainability should feature in future funding applications. Most respondents engaged in sustainability initiatives at a host institute and organisational level. However, 39 % of coordinating centres and 65 % of representative sites had none within clinical trials conducted by their organisation. The majority of respondents foresaw challenges to sustainability engagement including competing time pressure, staff attitudes and resource constraints. Of nine potential facilitators to engagement, funding, an evidence base for sustainable research practice and training were the leading themes.

CONCLUSION

In the first global survey of its kind, a third of respondents reported that climate change had impacted trial conduct. Integration of sustainability measures was absent in a significant minority. Funding and dedicated resourcing would facilitate increased engagement in cancer clinical trials.

摘要

背景

将可持续性措施纳入临床研究将减少与医疗保健相关的气候影响。

方法

我们评估了乳腺癌国际组织(BIG)成员的气候变化影响、现有的可持续性参与情况以及减缓气候变化战略的挑战和促进因素。开发了一项基于网络的30项调查问卷,用于评估气候影响、可持续性参与情况、参与的挑战和促进因素以及资金申请中的可持续性整合,并于2023年11月至2024年3月期间以电子方式分发。

结果

来自5大洲的34个成员(研究小组和数据中心)、参与站点以及BIG总部做出了回应。收到了来自21个组织的26份回复,来自17个参与站点的20份回复。28个小组未收到回复。三分之一的成员小组的试验开展受到了气候变化影响,如基础设施受损。78%的小组同意可持续性应在未来的资金申请中体现。大多数受访者在主办机构和组织层面参与了可持续性倡议。然而,在其组织进行的临床试验中,39%的协调中心和65%的代表站点没有开展相关活动。大多数受访者预见到可持续性参与面临挑战,包括竞争激烈的时间压力、工作人员态度和资源限制。在九个潜在的参与促进因素中,资金、可持续研究实践的证据基础和培训是主要主题。

结论

在同类首次全球调查中,三分之一的受访者报告称气候变化影响了试验开展。相当一部分人未将可持续性措施纳入其中。资金和专门的资源将有助于增加对癌症临床试验的参与。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db11/12020854/2ae0f14df622/gr1.jpg

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