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考察[具体植物名称]乙酸乙酯提取物作为COVID-19辅助疗法的疗效和安全性:一项随机、多中心、对照临床试验。 (注:原文中“as complementary therapy in COVID-19”前缺少具体植物名称,翻译时添加了[具体植物名称]以保证句子完整通顺)

Examining efficacy and safety of ethyl acetate extract from as complementary therapy in COVID-19: A randomized, multicenter, controlled clinical trial.

作者信息

Amin Mansour, Pouladzadeh Mandana, Yadyad Mohammad Jaafar, Roshanfard Roshanak, Pipelzadeh Mohamad Hasan, Talebi Afshin, Sharif Maakhmalzadeh Behzad, Bijanzadeh Mehdi, Rakipour Nasrin, Alizadehattar Gholamreza, Seyedian Seyed Saeed, Ahmadi Angali Kambiz, Moradi Choghakabodi Parastoo, Akbari Akbar, Maghsodi Fatemeh, Barzegari Ebrahim, Jamalan Maryam, Aalizadeh Reza, Jamalan Mostafa

机构信息

Department of Microbiology, Infection and Tropical Diseases Research Center, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Department of Emergency Medicine, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

出版信息

Avicenna J Phytomed. 2024 Nov-Dec;14(6):699-710. doi: 10.22038/AJP.2024.24523.

Abstract

OBJECTIVE

Given the apparent life-threatening nature of COVID-19, finding an effective treatment is under investigation.

MATERIALS AND METHODS

We assessed effect of shallomin oral syrup (co IranAmin) as a complementary treatment to improve the clinical outcomes in COVID-19 patients. Patients in the control group received the approved treatment protocol (lopinavir/ritonavir), while those in the intervention group were treated with the oral syrup shallomin in addition to the approved treatment. Clinical status of treated patients was recorded and compared.

RESULTS

There were meaningful differences between the two groups regarding shortened length of hospital stay and the recovery time for cough, myalgia, sore throat, and shortness of breath. No side effect occurred in the intervention group compared to the control group in terms of biochemical and hematological factors.

CONCLUSION

It seems that the treatment with shallomin syrup showed remarkable contribution to the recovery of COVID-19 induced symptoms in the patients under lopinavir/ritonavir therapy.

摘要

目的

鉴于新型冠状病毒肺炎(COVID-19)明显的危及生命的特性,正在研究寻找一种有效的治疗方法。

材料与方法

我们评估了沙洛明口服糖浆(Co IranAmin)作为辅助治疗改善COVID-19患者临床结局的效果。对照组患者接受批准的治疗方案(洛匹那韦/利托那韦),而干预组患者除批准的治疗外还接受沙洛明口服糖浆治疗。记录并比较接受治疗患者的临床状况。

结果

两组在缩短住院时间以及咳嗽、肌痛、咽痛和呼吸急促的恢复时间方面存在显著差异。与对照组相比,干预组在生化和血液学因素方面未出现副作用。

结论

似乎沙洛明糖浆治疗对接受洛匹那韦/利托那韦治疗的患者中COVID-19诱发症状的恢复有显著贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1306/12009622/5537e2a7008c/AJP-14-699-g001.jpg

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