Ounsted M K, Cockburn J M, Moar V A, Redman C W
Arch Dis Child. 1985 Jul;60(7):631-5. doi: 10.1136/adc.60.7.631.
At age 7.5 years the supine blood pressures of 216 children born to women who had been hypertensive during pregnancy were recorded. No associations were found between the blood pressures of the children and their mothers. The blood pressures of children whose mothers received methyldopa during pregnancy did not differ from those of children whose mothers had no specific treatment. Four boys whose mothers had taken methyldopa for more than 150 days had significantly lower systolic and diastolic pressures than those in whom the treatment had been of shorter duration. Significant findings from multiple regression analyses were: positive associations between boys' systolic and diastolic pressures and current weight, and diastolic pressure and maternal weight; negative associations between boys' systolic and diastolic pressures and birthweight; and a positive association between girls' systolic pressure and current weight.
在7.5岁时,记录了216名母亲孕期患高血压的儿童的仰卧位血压。未发现儿童血压与其母亲血压之间存在关联。母亲孕期服用甲基多巴的儿童血压与母亲未接受特殊治疗的儿童血压没有差异。母亲服用甲基多巴超过150天的4名男孩的收缩压和舒张压显著低于治疗时间较短的男孩。多元回归分析的显著结果为:男孩的收缩压和舒张压与当前体重、舒张压与母亲体重呈正相关;男孩的收缩压和舒张压与出生体重呈负相关;女孩的收缩压与当前体重呈正相关。