Sason Anat, Adelson Miriam, Potik David, Schreiber Shaul, Peles Einat
Dr. Miriam & Sheldon G. Adelson Clinic for Drug Abuse, Treatment & Research, Tel-Aviv Sourasky Medical Center, Tel Aviv, Israel.
Department of Criminology, Bar-Ilan University, Ramat-Gan, Israel.
Subst Abuse Rehabil. 2025 Apr 18;16:95-104. doi: 10.2147/SAR.S509821. eCollection 2025.
A war state followed the October 7th, 2003, Hamas vast attack on civilians and military in the southern part of Israel, requiring an immediate adaptation of the routine functioning of the methadone maintenance treatment (MMT) clinics - typically, through the expansion of the take-home dose (THD) policies.
To evaluate the level of anxiety and its relation to patients' satisfaction regarding THD expansion one month post-attack.
Of the 320 current patients in one MMT clinic, 297 (92.8%) were interviewed for anxiety (GAD-7) and rated whether the THD expansion benefited them (1 to 5). Substance in urine, sociodemographic, and addiction history details were taken.
Of the participants, 35% were found to have no anxiety, 22.2% with mild, 21.9% with moderate, and 20.9% had severe anxiety. Logistic regression for anxiety found cocaine in urine and not opioids in urine (Odds Ratio (OR) = 3.6), history of having experienced physical violence (OR = 1.8), and not working (OR = 2.1) as risk factors. THD expansion benefited (scored ≥ 4) 82.2% of the responders, and in logistic regression for severe anxiety, not satisfied with THD expansion (OR = 2.9), being Israeli born (OR = 2.1), and not working (OR = 2.5) were included. Substance use did not change pre- and post-Hamas attack.
Most patients were satisfied with the THD expansion. However, severe anxiety levels characterized those who were not, emphasizing the need for anxiety monitoring to determine those patients. Additional intervention and augmenting these patients' frequency of visits to the clinic (instead of THD expansion) is recommended so they have further meetings with their therapist and reduce their anxiety.
2003年10月7日哈马斯对以色列南部平民和军队发动大规模袭击后,进入战争状态,这要求美沙酮维持治疗(MMT)诊所立即调整日常运作——通常是通过扩大带回家剂量(THD)政策。
评估袭击发生一个月后患者的焦虑水平及其与对THD扩大满意度的关系。
在一家MMT诊所的320名现患患者中,297名(92.8%)接受了焦虑(广泛性焦虑障碍7项量表)访谈,并对THD扩大是否对他们有益进行评分(1至5分)。采集了尿液中的物质、社会人口统计学和成瘾史细节。
在参与者中,35%被发现无焦虑,22.2%为轻度焦虑,21.9%为中度焦虑,20.9%为重度焦虑。焦虑的逻辑回归分析发现,尿液中含有可卡因而非阿片类物质(优势比(OR)=3.6)、有身体暴力史(OR = 1.8)以及无工作(OR = 2.1)是危险因素。THD扩大使82.2%的应答者受益(得分≥4),在重度焦虑的逻辑回归分析中,对THD扩大不满意(OR = 2.9)、以色列出生(OR = 2.1)以及无工作(OR = 2.5)被纳入分析。哈马斯袭击前后物质使用情况未发生变化。
大多数患者对THD扩大感到满意。然而,不满意的患者表现出重度焦虑水平,这凸显了监测焦虑以确定这些患者的必要性。建议进行额外干预并增加这些患者到诊所就诊的频率(而非扩大THD),以便他们能与治疗师进一步会面并减轻焦虑。