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欧洲痴呆症患病率的统一估计因儿童时期受教育程度的不同而有很大差异。

Harmonized prevalence estimates of dementia in Europe vary strongly with childhood education.

作者信息

Börsch-Supan Axel, Douhou Salima, Otero Marcela C, Tawiah Beatrice Baaba

机构信息

Max Planck Institute for Social Law and Social Policy, Munich, Germany.

Munich Research Institute for the Economics of Aging and SHARE Analyses, Leopoldstrasse 139, 80804, Munich, Germany.

出版信息

Sci Rep. 2025 Apr 23;15(1):14024. doi: 10.1038/s41598-025-97691-z.

Abstract

Up-to-date, strictly cross-nationally comparable and nationally representative data on cognitive health are essential for our understanding of the dementia-related challenges in healthcare, to detect shortcomings in healthcare systems and to design effective prevention strategies. Such data have been missing in Europe. We use the most recent 2022 wave of the strictly harmonized Survey of Health, Ageing and Retirement in Europe (SHARE, 47,773 individuals age 65 and older) to obtain prevalence estimates of mild cognitive impairment and dementia for 27 European countries and Israel in 2022. The novelty of the paper is to validate these estimates using the Harmonized Cognitive Assessment Protocol (HCAP) as a validation tool. These new data exhibit much higher prevalence rates of dementia in the Mediterranean and Southeastern European countries and a much larger variation of cognitive impairment across Europe and Israel than previously known. Dementia prevalence ranges from 4.5% in Switzerland to 22.7% in Spain, MCI prevalence from 17.2% in Sweden to 31.1% in Portugal. Most of this variation can be explained by differences in education when respondents were young. Prevalence rates vary plausibly with other risk factors such as age and comorbidities associated with dementia.

摘要

关于认知健康的最新、严格跨国可比且具有全国代表性的数据,对于我们理解医疗保健中与痴呆症相关的挑战、发现医疗保健系统的缺陷以及设计有效的预防策略至关重要。欧洲一直缺少此类数据。我们利用欧洲健康、老龄化和退休状况调查(SHARE,2022年最新一轮,47773名65岁及以上个体)的严格统一数据,得出2022年27个欧洲国家和以色列轻度认知障碍和痴呆症的患病率估计值。本文的新颖之处在于使用统一认知评估协议(HCAP)作为验证工具来验证这些估计值。这些新数据显示,地中海和东南欧国家的痴呆症患病率要高得多,而且整个欧洲和以色列的认知障碍差异比之前所知的要大得多。痴呆症患病率从瑞士的4.5%到西班牙的22.7%不等,轻度认知障碍患病率从瑞典的17.2%到葡萄牙的31.1%不等。这种差异大部分可以用受访者年轻时受教育程度的不同来解释。患病率也与其他风险因素(如年龄和与痴呆症相关的合并症)合理相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/604a/12019132/d0c9889ba8aa/41598_2025_97691_Fig1_HTML.jpg

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