Nejatifar Zahra, Alizadeh Ahad, Amerzadeh Mohammad, Omidian Shideh, Rafiei Sima
Student Research Committee, School of Health, Qazvin University of Medical Sciences, Qazvin, Iran.
Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
J Health Popul Nutr. 2025 Apr 23;44(1):133. doi: 10.1186/s41043-025-00841-2.
Palliative care is a key component of integrated care to improve care quality and reduce hospitalization costs for patients with chronic obstructive pulmonary disease (COPD). This study aims to use machine learning algorithms to create an effective approach to the early recognition and identification of frailty as a long-term condition in COPD patients.
The level of frailty in a sample of patients (total n = 140) was assessed using the checklist of frailty assessment, which encompasses five questions: measured decrease in body mass index (BMI), fatigue status, physical activity status, and walking speed. The last question assessed disability through forced expiratory volume in the first second (FEV1) measured using spirometry results. The next checklist was the Palliative Care Needs Assessment Tool, taken from the assessment checklist for palliative care needs in patients with COPD by Thoenesen et al. [28]. We used different machine learning algorithms, with performance assessed using an area under the receiver-operating characteristic curve, sensitivity, and specificity, to develop a validated set of criteria for frailty using machine learning.
Study findings revealed that the palliative care needs assessment tool categorized 74% of all patients into two groups: those requiring palliative care and those not requiring it. Furthermore, the influential variables that contributed to predicting the need for palliative care included measured BMI reduction, fatigue status, physical activity level, slow walking, and FEV1. The super-learning model demonstrated higher accuracy (92%) than other machine-learning algorithms.
The study highlights the need for more collaboration between clinicians and data scientists to use the potential of data collected from COPD patients in clinical settings with the purpose of early identification of frailty as a long-term condition. Predicting palliative care needs accurately is critical in these contexts, as it can lead to better resource allocation, improved healthcare delivery, and enhanced patient outcomes.
姑息治疗是综合护理的关键组成部分,可提高慢性阻塞性肺疾病(COPD)患者的护理质量并降低住院费用。本研究旨在使用机器学习算法创建一种有效的方法,用于早期识别和确定COPD患者的虚弱这一长期状况。
使用虚弱评估清单对一组患者样本(共140例)的虚弱程度进行评估,该清单包含五个问题:测量的体重指数(BMI)下降、疲劳状态、身体活动状态和步行速度。最后一个问题通过使用肺活量测定结果测量的第一秒用力呼气量(FEV1)来评估残疾情况。下一个清单是姑息治疗需求评估工具,取自Thoenesen等人[28]的COPD患者姑息治疗需求评估清单。我们使用了不同的机器学习算法,并通过受试者操作特征曲线下面积、敏感性和特异性来评估性能,以使用机器学习开发一套经过验证的虚弱标准。
研究结果显示,姑息治疗需求评估工具将所有患者中的74%分为两组:需要姑息治疗的患者和不需要姑息治疗的患者。此外,有助于预测姑息治疗需求的影响变量包括测量的BMI降低、疲劳状态、身体活动水平、步行缓慢和FEV1。超级学习模型显示出比其他机器学习算法更高的准确率(92%)。
该研究强调临床医生和数据科学家需要加强合作,以利用在临床环境中从COPD患者收集的数据的潜力,以便早期识别虚弱这一长期状况。在这些情况下,准确预测姑息治疗需求至关重要,因为这可以导致更好的资源分配、改善医疗服务提供并提高患者预后。