Wayesa Gemechisa Akuma, Berhanu Wedajo Mitiku, Demissie Wondu Reta, Belay Gizaw Admasu, Hika Gudeta Assefa, Gudina Gula Guteta
Department of Anesthesia, Institute of Health Science, Wallaga University, Nekemte, Ethiopia.
Department of Anesthesia, Institute of Health Science, Jimma University, Jimma, Ethiopia.
Perioper Med (Lond). 2025 Apr 24;14(1):48. doi: 10.1186/s13741-025-00520-0.
Extubation refers to removing the breathing tube from the patient's airway after surgery under general anesthesia with tracheal intubation. Extubation procedures typically take less than 15 min, and if they take more, they are prolonged. Whether or not to extubate a patient depends on several factors, including the patient's preoperative status, the type of surgery, anesthetic methods, and expected recovery after the procedure. Thus, the study's objective was to determine the incidence of prolonged extubation and its associated factors among adult patients undergoing surgery at Jimma Medical Center.
A prospective observational study through a consecutive sampling technique was conducted. Ethical clearance and approval were obtained from the institutional review board of Jimma University. Data on the extubation time and possible associated factors for a prolonged extubation time were collected using a data collection checklist. After being entered into EpiData 4.6 and exported into SPSS 25, descriptive analyses and logistic regression were carried out. In multivariate variables, p ≤ 0.05 was declared as statistical significance.
Three-hundred eight adult patients were enrolled in the current study. Of these, the incidence of prolonged extubation was 24.7% (95% CI [20.0-29.9]). The identified associated factors were age ≥ 55 years (AOR = 5.7, 95% CI [2.62, 12.69], p ≤ 001); ASAPS > II (AOR = 4.27, 95% CI [1.59, 11.45], p = 004); BMI ≥ 30 kg/m (AOR = 6.6, 95% CI [2.37, 18.36], p ≤ 001); the use of benzodiazepine (AOR = 3.43, 95% CI [1.42, 8.25], p = 0.006); using of isoflurane (AOR = 0.35, 95% CI [0.15, 0.78], p = 0.011); prone position (AOR = 4.68, 95% CI [1.56, 14.07], p = 0.006); extubation in afternoon (AOR = 2.69, 95% CI [1.26, 5.74]; p = 0.011); and duration of surgery ≥ 210 min (AOR = 5.2, 95% CI [2.32, 11.72], p ≤ 0.001).
The study found that prolonged time to extubation occurred in one-fourth of the patients. The independent factors statistically associated with prolonged extubation were older ages, higher ASA class, obesity (≥ 30 kg/m), the use of benzodiazepine, halothane for maintenance, prone position, extubation in the afternoon, and longer procedures (≥ 210 min).
拔管是指在全身麻醉气管插管手术后从患者气道移除呼吸管。拔管过程通常少于15分钟,如果超过这个时间,则为延长拔管时间。是否对患者进行拔管取决于几个因素,包括患者的术前状况、手术类型、麻醉方法以及术后预期恢复情况。因此,本研究的目的是确定吉马医疗中心接受手术的成年患者中延长拔管的发生率及其相关因素。
采用连续抽样技术进行前瞻性观察研究。获得了吉马大学机构审查委员会的伦理批准。使用数据收集清单收集拔管时间及延长拔管时间可能的相关因素的数据。数据录入EpiData 4.6并导出到SPSS 25后,进行描述性分析和逻辑回归。在多变量分析中,p≤0.05被视为具有统计学意义。
本研究纳入了308例成年患者。其中,延长拔管的发生率为24.7%(95%可信区间[20.0 - 29.9])。确定的相关因素为年龄≥55岁(比值比[AOR]=5.7,95%可信区间[2.62, 12.69],p≤0.001);美国麻醉医师协会身体状况评分(ASAPS)>Ⅱ级(AOR = 4.27,95%可信区间[1.59, 11.45],p = 0.004);体重指数(BMI)≥30 kg/m²(AOR = 6.6,95%可信区间[2.37, 18.36],p≤0.001);使用苯二氮䓬类药物(AOR = 3.43,95%可信区间[1.42, 8.25],p = 0.006);使用异氟烷(AOR = 0.35,95%可信区间[0.15, 0.78],p = 0.011);俯卧位(AOR = 4.68,95%可信区间[1.56, 14.07],p = 0.006);下午拔管(AOR = 2.69,95%可信区间[1.26, 5.74];p = 0.011);手术时间≥210分钟(AOR = 5.2,95%可信区间[2.32, 11.72],p≤0.001)。
该研究发现四分之一的患者出现延长拔管时间。与延长拔管在统计学上相关的独立因素为年龄较大、ASA分级较高、肥胖(≥30 kg/m²)、使用苯二氮䓬类药物、使用氟烷维持麻醉、俯卧位、下午拔管以及手术时间较长(≥210分钟)。