用于引导组织再生和引导骨再生的生物材料：综述

Biomaterials for Guided Tissue Regeneration and Guided Bone Regeneration: A Review.

作者信息

Duarte Nathália Dantas, Frigério Paula Buzo, Chica Gloria Estefania Amaya, Okamoto Roberta, Buchaim Rogério Leone, Buchaim Daniela Vieira, Messora Michel Reis, Issa João Paulo Mardegan

机构信息

Department of Diagnosis and Surgery, Araçatuba School of Dentistry (FOA-UNESP), São Paulo State University, Araçatuba 16015-050, Brazil.

Department of Oral and Maxillofacial Surgery and Periodontology, Ribeirão Preto School of Dentistry (FORP-USP), University of São Paulo, Ribeirão Preto 14090-904, Brazil.

出版信息

Dent J (Basel). 2025 Apr 21;13(4):179. doi: 10.3390/dj13040179.

DOI:10.3390/dj13040179

PMID:40277509

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12026320/

Abstract

This review aims to provide an overview of the types of membranes, bone substitutes, and mucosal substitutes used for GTR and GBR and briefly explores recent innovations for tissue regeneration and their future perspectives. Since this is a narrative review, no systematic search, meta-analysis, or statistical analysis was conducted. Using biomaterials for GTR and GBR provides a reduction in postoperative morbidity, as it contributes to less invasive clinical procedures, serving as an alternative to autogenous grafts. Moreover, randomized clinical trials (RCTs) and systematic reviews are essential for the evaluation of new biomaterials. These studies provide more robust evidence and help guide clinical practice in the selection of safer and more effective biomaterials, allowing for the personalization of treatment protocols for each patient.

摘要

本综述旨在概述用于引导组织再生（GTR）和引导骨组织再生（GBR）的膜、骨替代物和黏膜替代物的类型，并简要探讨组织再生的最新创新及其未来前景。由于这是一篇叙述性综述，未进行系统检索、荟萃分析或统计分析。将生物材料用于GTR和GBR可降低术后发病率，因为它有助于减少侵入性临床操作，可作为自体移植物的替代物。此外，随机临床试验（RCT）和系统评价对于评估新型生物材料至关重要。这些研究提供了更有力的证据，并有助于指导临床实践中选择更安全、更有效的生物材料，从而实现针对每位患者的治疗方案个性化。