移动教育平台对肾病综合征和类固醇诱导型糖尿病患者血糖控制的积极影响：一项随机对照研究。

Positive impact of mobile educational platforms on blood glucose control in patients with nephrotic syndrome and steroid-induced diabetes mellitus: a randomized controlled study.

作者信息

Yang Zhimin, Tan Zhicheng, Sun Minna, Zhang Jing, Hou Haizhu, Li Xin

机构信息

Department of Nephrology, The Fifth Clinical Medical College of Shanxi Medical University; Shanxi Provincial People's Hospital, No. 359 Heping North Road, Jiancaoping District, Taiyuan, Shanxi Province, 030000, China.

出版信息

BMC Endocr Disord. 2025 Apr 27;25(1):118. doi: 10.1186/s12902-024-01802-2.

DOI:10.1186/s12902-024-01802-2

PMID:40287747

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12034120/

Abstract

OBJECTIVE

Steroid-induced diabetes mellitus (SDM) is a common complication in patients with nephrotic syndrome (NS) undergoing steroid therapy. Effective blood glucose control is critical for improving outcomes in these patients. This study evaluates the impact of mobile educational platforms on blood glucose control and patient adherence in patients with NS combined with SDM.

METHODS

A randomised controlled study was conducted involving 56 patients with NS and SDM at Shanxi People's Hospital between April 2019 and December 2020. Participants were recruited using convenient sampling and were randomly assigned to either the intervention group (n = 28) or the control group (n = 28). The control group received routine health management, whereas the experimental group was provided with health management via a mobile educational platform. Blood glucose levels (fasting glucose and postprandial blood glucose), self-management efficacy and patient adherence to treatment were assessed over a 6-month period.

RESULTS

The 56 participants included in the study had a mean age of 69.0 ± 10.5 years and an average diabetes duration of 7.2 ± 3.5 years. At the end of 6 months, the intervention group showed significant reductions in fasting blood glucose and postprandial blood glucose levels (P < 0.001). Self-management efficacy, assessed using the Diabetes Self-Efficacy Scale, improved significantly post-intervention (4.42 ± 0.53 vs. 4.15 ± 0.56, P = 0.020). Additionally, patient adherence to treatment improved by 25% in the intervention group compared with the control group.

CONCLUSION

The use of mobile educational platforms significantly resulted in better glycemic control and treatment adherence in the patients with NS and SDM compared to the control group. These findings suggest that integrating mobile health technologies into routine care can enhance disease management and optimise outcomes.

TRIAL REGISTRATION

The study was retrospectively registered "ISRCTN23135945" on 05/11/2024.

摘要

目的

类固醇诱导的糖尿病（SDM）是肾病综合征（NS）患者接受类固醇治疗时常见的并发症。有效控制血糖对于改善这些患者的预后至关重要。本研究评估移动教育平台对NS合并SDM患者血糖控制和患者依从性的影响。

方法

2019年4月至2020年12月期间，在山西省人民医院对56例NS合并SDM患者进行了一项随机对照研究。采用方便抽样法招募参与者，并将其随机分为干预组（n = 28）和对照组（n = 28）。对照组接受常规健康管理，而实验组通过移动教育平台进行健康管理。在6个月的时间里评估血糖水平（空腹血糖和餐后血糖）、自我管理效能和患者治疗依从性。

结果

纳入研究的56名参与者的平均年龄为69.0±10.5岁，平均糖尿病病程为7.2±3.5年。6个月末，干预组的空腹血糖和餐后血糖水平显著降低（P < 0.001）。使用糖尿病自我效能量表评估的自我管理效能在干预后显著改善（4.42±0.53对4.15±0.56，P = 0.020）。此外，与对照组相比，干预组患者的治疗依从性提高了25%。