Cai Mandi, Ma Rencai, Chen Junlin, Huang Xinzhao, Zhang Yixing, Xie Zhuohang, Zou Xiaobao, Ma Xiangyang
The First School of Clinical Medicine, Southern Medical University, No.1838 North of Guangzhou Road, Guangzhou, 510515, People's Republic of China.
Department of Orthopedics, General Hospital of Southern Theatre Command of PLA, 111 Liuhua Road, Guangzhou, 510010, People's Republic of China.
J Orthop Surg Res. 2025 Apr 29;20(1):428. doi: 10.1186/s13018-025-05723-1.
C1-C2 pedicle screw-rod fixation (PSR) is widely used for atlantoaxial dislocations. However, its limited reduction capacity in refractory cases necessitates additional release surgeries, increasing operative risks including prolonged surgical time and expanded tissue damage. We developed a novel Z-shaped anti-rotation rod to improve reduction capability, but its biomechanical performance requires evaluation.
A nonlinear atlantoaxial instability three-dimensional (3D) C0-C3 finite element model was constructed using computed tomography images from a 25-year-old healthy male without a history of cervical spine diseases. Based on this model, two C1-C2 fixation configurations were simulated: conventional pedicle screw-rod (PS-CR) and pedicle screw-Z-shaped rod (PS-ZR). Reduction forces were measured and compared. Range of motion (ROM), stress distribution and peak stress values of the implants were recorded and compared under six loading conditions including flexion, extension, lateral bending, and axial rotation.
Both configurations achieved a greater than 98% reduction in the C1-C2 segmental ROM, with similar compensatory motions in adjacent segments. The reduction force of PS-ZR showed significant advantages (2-8 mm range), achieving a maximum reduction force of 88.544 N, which is 1.67 to 3.68 times that of PS-CR. The PS-ZR system experiences greater stress compared to the PS-CR system, escalating with Z-rod height. Regarding stress distribution and peak values of rods, the maximum stress on the PS-CR system was mainly concentrated at the connection between the rod and the screw nut while the maximum stress on the PS-ZR system was concentrated at the transition part of the "Z" shape.
Both PS-CR and PS-ZR configurations provide reliable and comparable stability. Compared to the PS-CR configuration, the PS-ZR configuration provides superior reduction force and stability, potentially reducing the need for additional release surgery and surgical time. This novel design has significant clinical implications for improving fixation techniques.
C1-C2椎弓根螺钉-棒固定术(PSR)广泛应用于寰枢椎脱位。然而,在难治性病例中其复位能力有限,需要额外的松解手术,这增加了手术风险,包括手术时间延长和组织损伤扩大。我们研发了一种新型Z形抗旋转棒以提高复位能力,但其生物力学性能需要评估。
使用一名25岁无颈椎疾病史的健康男性的计算机断层扫描图像构建非线性寰枢椎不稳定三维(3D)C0-C3有限元模型。基于该模型,模拟了两种C1-C2固定构型:传统椎弓根螺钉-棒(PS-CR)和椎弓根螺钉-Z形棒(PS-ZR)。测量并比较复位力。记录并比较在包括前屈、后伸、侧弯和轴向旋转在内的六种加载条件下植入物的活动范围(ROM)、应力分布和峰值应力值。
两种构型均使C1-C2节段ROM减少超过98%,相邻节段的代偿运动相似。PS-ZR的复位力显示出显著优势(2-8毫米范围),最大复位力达到88.544牛,是PS-CR的1.67至3.68倍。与PS-CR系统相比,PS-ZR系统承受的应力更大,且随Z形棒高度增加而升高。关于棒的应力分布和峰值,PS-CR系统的最大应力主要集中在棒与螺母的连接处,而PS-ZR系统的最大应力集中在“Z”形的过渡部分。
PS-CR和PS-ZR构型均提供可靠且可比的稳定性。与PS-CR构型相比,PS-ZR构型提供了更好的复位力和稳定性,可能减少额外松解手术的需求和手术时间。这种新颖的设计对改进固定技术具有重要的临床意义。