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一种用于儿童1型糖尿病的新型随访模式可实现更好的血糖控制。

A Novel Follow-Up Model for Type 1 Diabetes in Children Leads to Higher Glycemic Control.

作者信息

Vonasek Julia, Larsen Isabelle M, Nikontovic Amar, Thorvig Camilla Maria

机构信息

Pediatric Department, North Denmark Regional Hospital, Hjørring, Denmark.

Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark.

出版信息

Pediatr Diabetes. 2025 Jan 7;2025:6920068. doi: 10.1155/pedi/6920068. eCollection 2025.

Abstract

Poor glycemic control in type 1 diabetes (T1D) in children leads to a higher risk of diabetic complications. In the pediatric department at the North Denmark Regional Hospital, only one-third of all children with diabetes were well-regulated, defined as HbA no more than 58 mmol/mol (7.5%), in 2016. Therefore, a novel follow-up model was developed to increase the proportion of children with well-regulated T1Ds. The aim of this study was to evaluate the effect of a standardized follow-up model for poorly regulated diabetes on mean HbA. All children aged 0-18 with T1Ds were included in this study. A novel standardized follow-up model was developed if HbA was greater than 58 mmol/mol (7.5%), in which children were followed more closely until improvement in glycemic control. In the reference year, only one-third of children with diabetes were well-regulated and 19% were poorly regulated (HbA greater than 75 mmol/mol (9.0%)). After fully implementing the model, two-thirds of the children had well-regulated diabetes, and only a few percent had poorly regulated diabetes. The mean HbA decreased by almost 10 mmol/mol (or 0.8%) from the reference year to the following years when the model was fully implemented. This follow-up model for poorly regulated diabetes increased the fraction of children with well-regulated diabetes in our clinic and significantly decreased mean HbA.

摘要

儿童1型糖尿病(T1D)患者血糖控制不佳会导致糖尿病并发症风险升高。2016年,在北丹麦地区医院儿科,所有糖尿病患儿中只有三分之一的血糖得到良好控制,即糖化血红蛋白(HbA)不超过58 mmol/mol(7.5%)。因此,开发了一种新型随访模式,以提高T1D血糖控制良好患儿的比例。本研究旨在评估针对血糖控制不佳的糖尿病的标准化随访模式对平均HbA的影响。本研究纳入了所有0至18岁的T1D患儿。如果HbA大于58 mmol/mol(7.5%),则开发一种新型标准化随访模式,在此模式下对患儿进行更密切的随访,直至血糖控制得到改善。在参照年份,只有三分之一的糖尿病患儿血糖控制良好,19%的患儿血糖控制不佳(HbA大于75 mmol/mol(9.0%))。在全面实施该模式后,三分之二的患儿糖尿病得到良好控制,只有百分之几的患儿血糖控制不佳。从参照年份到该模式全面实施后的次年,平均HbA下降了近10 mmol/mol(或0.8%)。这种针对血糖控制不佳的糖尿病的随访模式提高了我们诊所中糖尿病得到良好控制的患儿比例,并显著降低了平均HbA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f0a/12017064/66845594032d/PEDI2025-6920068.001.jpg

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