Henriques Andreia, Venda João, Ferreira Emanuel, Oliveira Nuno A
Nephrology, Centro Hospitalar e Universitário de Coimbra, Coimbra, PRT.
Interventional Nephrology, Centro de Acesso Vascular SANFIL, Coimbra, PRT.
Cureus. 2025 Mar 31;17(3):e81496. doi: 10.7759/cureus.81496. eCollection 2025 Mar.
Background Vascular access (VA) dysfunction in hemodialysis (HD) significantly impacts patient outcomes. While percutaneous transluminal angioplasty remains the primary intervention, covered stents (CSs) have emerged as a valuable adjunct. This study evaluates the efficacy of CS in reducing reinterventions and delaying subsequent procedures. Methods This retrospective study included patients who underwent their first CS placement at the SANFIL Vascular Access Centre between 2017 and 2022, involving arteriovenous fistulas (AVFs) and arteriovenous grafts (AVGs). The primary outcome was a comparison of the number of procedures 12 months before and after CS placement. Secondary outcomes assessed primary patency (PP), assisted primary patency (APP), secondary patency (SP), and factors influencing these outcomes. Results Eleven patients were included, 72.7% male, with a mean age of 74.6 ± 8.8 years. Seven (63.6%) patients had an AVF. In the 12 months after CS placement, only two VAs did not require reintervention, while the remaining nine exhibited CS-related dysfunctions. The mean number of interventions in the 12 months before and after CS placement was similar (1.73 ± 1.01 and 1.64 ± 1.63, respectively; p = 0.85). However, the mean time to reintervention after CS placement was longer than the previous intervention: 6.22 ± 3.67 and 2.63 ± 2.60 months, respectively. PP was significantly higher in AVFs than in AVGs. Conclusions CS placement may delay the need for subsequent interventions, but it does not significantly reduce the frequency of procedures or improve overall VA survival. The decision to deploy a CS should be made on a case-by-case basis, particularly for patients with limited vascular options or those who are unable to undergo additional surgical procedures. Careful patient selection is essential to ensure the optimal use of CS in HD patients.
背景 血液透析(HD)中的血管通路(VA)功能障碍会显著影响患者的治疗结果。虽然经皮腔内血管成形术仍然是主要干预手段,但覆膜支架(CSs)已成为一种有价值的辅助手段。本研究评估了CS在减少再次干预和推迟后续手术方面的疗效。方法 这项回顾性研究纳入了2017年至2022年期间在圣菲血管通路中心首次置入CS的患者,包括动静脉内瘘(AVF)和动静脉移植物(AVG)。主要结局是比较CS置入前后12个月的手术次数。次要结局评估了原发性通畅率(PP)、辅助原发性通畅率(APP)、继发性通畅率(SP)以及影响这些结局的因素。结果 共纳入11例患者,男性占72.7%,平均年龄为74.6±8.8岁。7例(63.6%)患者有AVF。在CS置入后的12个月内,只有2个VA不需要再次干预,而其余9个出现了与CS相关的功能障碍。CS置入前后12个月的平均干预次数相似(分别为1.73±1.01和1.64±1.63;p=0.85)。然而,CS置入后再次干预的平均时间比上一次干预更长:分别为6.22±3.67个月和2.63±2.60个月。AVF的PP显著高于AVG。结论 CS置入可能会推迟后续干预的需求,但并不能显著降低手术频率或提高整体VA生存率。CS的部署应根据具体情况决定,特别是对于血管选择有限或无法接受额外手术的患者。仔细选择患者对于确保HD患者最佳使用CS至关重要。