Katongole Simon Peter, Mukama Semei Christopher, Nakawesi Jane, Bindeeba Dedrix Stephenson, Ezajobo Simons, Nakubulwa Susan, Mugisa Andrew, Odiit Mary, Senyimba Catherine, Namitala Eve, Anguyo Robert D D M Onzima, Mukasa Barbara
Gudie University Project, P.O. Box 27450, Kampala, Uganda.
Mildmay Uganda, Kampala, Uganda.
BMC Infect Dis. 2025 May 5;25(1):659. doi: 10.1186/s12879-025-11013-2.
Sexually transmitted infections (STIs) are a major global public health problem, associated with infertility, adverse pregnancy outcomes, and significant social and economic burdens. These challenges are particularly severe in underprivileged communities. A 2024 World Health Organisation report highlighted a global surge in STIs, requiring intensified efforts to improve their control and management. In order to appropriately respond and reverse the status quo, it is important to understand the extent to which the current interventions have reached the beneficiaries. This study aimed to assess the coverage of sexually transmitted infection (STI) services using the Lot Quality Assurance Sampling (LQAS) approach in eight districts of Central Uganda.
A household survey was conducted in eight districts, targeting four population groups: mothers of children aged 0-11 months, women aged 15-49 years, men aged 15 + years, and youth aged 15-25 years. LQAS was used, with each district stratified into five supervision areas (SAs). In each SA, 19 respondents were randomly sampled from each target group. The survey assessed key indicators related to STIs, including knowledge of STI symptoms, knowledge of actions to take when infected with an STI, and engagement in risky sexual behavior. The study also examined condom use during risky sex, circumcision acceptance and non-acceptance among men, including reasons for its acceptance or non-acceptance. Overall and district-specific coverage was calculated with 95% confidence intervals. Indicator coverage in the SAs was classified using LQAS decision rules (DRs) for each indicator, using the overall coverage as benchmark for setting the DR.
The findings revealed that mothers of children aged 0-11 months demonstrated superior knowledge of STIs and appropriate actions to take if one has an STI. Men (15 + years) and youth (15-24 years) reported engaging more in risky sexual behavior compared to women 15-49 years and mothers of children aged 0-11 months. Relatedly, men 15 + years reported higher condom use during risky intercourse. Youth were more likely to be circumcised than older men. Coverage for most indicators varied across SAs and districts. However, one in forty of the SAs fell short of average coverage in all the indicators. Personal hygiene was the leading motivator for circumcision acceptance while fear of pain was the leading driver for refusal to accept being circumcised.
The findings highlight vital disparities in STI knowledge and risky sexual behavior among different demographic groups. These findings inform public health strategies to address STI disparities and improve reproductive health outcomes. District and SA-specific bottleneck analysis is recommended in order to provide actionable solutions to improve low-indicator coverage in low-coverage districts and SAs.
性传播感染(STIs)是一个重大的全球公共卫生问题,与不孕症、不良妊娠结局以及巨大的社会和经济负担相关。这些挑战在贫困社区尤为严峻。2024年世界卫生组织的一份报告强调了全球性传播感染病例的激增,这就需要加大力度改善其控制和管理。为了做出适当回应并扭转现状,了解当前干预措施惠及受益人的程度非常重要。本研究旨在采用批质量保证抽样(LQAS)方法评估乌干达中部八个地区性传播感染(STI)服务的覆盖情况。
在八个地区开展了一项家庭调查,目标人群为四类:0至11个月儿童的母亲、15至49岁的女性、15岁及以上的男性以及15至25岁的青年。采用了LQAS方法,每个地区分为五个监督区域(SAs)。在每个监督区域,从每个目标群体中随机抽取19名受访者。该调查评估了与性传播感染相关的关键指标,包括对性传播感染症状的了解、感染性传播感染时应采取的行动的知识,以及参与危险性行为的情况。该研究还调查了危险性行为期间的避孕套使用情况、男性对包皮环切术的接受和不接受情况,包括接受或不接受的原因。计算了总体覆盖率和各地区的覆盖率,并给出95%的置信区间。根据LQAS决策规则(DRs)对各监督区域的指标覆盖率进行分类,以总体覆盖率作为设定决策规则的基准。
研究结果显示,0至11个月儿童的母亲对性传播感染及感染后应采取的适当行动有更丰富的知识。与15至49岁的女性和0至11个月儿童的母亲相比,15岁及以上的男性和15至24岁的青年报告称更多地参与危险性行为。与此相关的是,15岁及以上的男性报告在危险性交期间使用避孕套的比例更高。青年比年长男性更有可能接受包皮环切术。大多数指标的覆盖率在不同的监督区域和地区有所不同。然而,每四十个监督区域中有一个在所有指标上均未达到平均覆盖率。个人卫生是接受包皮环切术的主要动机,而害怕疼痛是拒绝接受包皮环切术的主要原因。
研究结果突出了不同人口群体在性传播感染知识和危险性行为方面的重大差异。这些发现为解决性传播感染差异和改善生殖健康结果的公共卫生策略提供了参考。建议进行地区和监督区域特定的瓶颈分析,以便为改善低覆盖率地区和监督区域的低指标覆盖率提供可采取行动的解决方案。