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Int J Surg. 2023 May 1;109(5):1539-1542. doi: 10.1097/JS9.0000000000000140.
2
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Cureus. 2023 Jan 7;15(1):e33493. doi: 10.7759/cureus.33493. eCollection 2023 Jan.
3
ACR Appropriateness Criteria® Ataxia-Child.ACR 适宜性标准® 儿童共济失调
J Am Coll Radiol. 2022 Nov;19(11S):S240-S255. doi: 10.1016/j.jacr.2022.09.010.
4
The impact of COVID-19 on patients with neurological disorders and their access to healthcare in Africa: A review of the literature.COVID-19 对非洲神经障碍患者及其获得医疗保健的影响:文献综述。
Brain Behav. 2022 Sep;12(9):e2742. doi: 10.1002/brb3.2742. Epub 2022 Aug 11.
5
Neurological disorders in HIV: Hope despite challenges.HIV 相关神经障碍:挑战虽大,希望犹存。
Immun Inflamm Dis. 2022 Mar;10(3):e591. doi: 10.1002/iid3.591. Epub 2022 Feb 10.
6
Friedreich ataxia in a family from Mali, West Africa/Friedreich ataxia in a Malian family.来自西非马里一个家族的弗里德赖希共济失调症/一个马里家族的弗里德赖希共济失调症
Clin Case Rep. 2021 Mar 24;9(5):e04065. doi: 10.1002/ccr3.4065. eCollection 2021 May.
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Nutrients. 2019 Feb 12;11(2):380. doi: 10.3390/nu11020380.

非洲的共济失调:当前的努力与建议

Ataxia in Africa: current efforts and recommendations.

作者信息

Nebieridze Anano, Uwishema Olivier, Jaafer Al Tarawneh Yusuf, I Abdelsamea Amir, Zrara Nancy, Albright Belise Mugabekazi, Mshaymesh Sarah

机构信息

Department of Research and Education, Oli Health Magazine Organization, Kigali, Rwanda.

Faculty of Medicine, David Tvildiani Medical University, Tbilisi, Georgia.

出版信息

Ann Med Surg (Lond). 2025 Apr 2;87(5):2800-2803. doi: 10.1097/MS9.0000000000003220. eCollection 2025 May.

DOI:10.1097/MS9.0000000000003220
PMID:40337411
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12055057/
Abstract

Ataxia which is a disorder of the nervous system with the primary symptom being unsteady mobility is becoming more prevalent especially within the African continent. Nonetheless, it is suggested that there may be more cases of ataxia that are still undiagnosed roughly and this has to do with very few health care facilities offering genetic testing. This disease is most commonly associated with a variety of neurological illnesses, including stroke and brain damage leading to the uncontrollable moving of the limbs. However, in Africa, the primary contributors to the increase in ataxia are infectious diseases and food scarcity caused by drought. In our article, we analyze the different types of ataxia according to their epidemiology and describe how sociological factors aggravate the situation. We detail existing national strategies and programs aimed at solving this problem, particularly increasing funding for the infrastructure necessary for genetic testing, imagining and brain studies. Even with these measures, there remain a number of gaps with regard to epidemiology studies that need painting so as aid in accurating in the diagnosis. Awareness of the problem regarding patient education and active healthcare personnel has to be raised too. We advocate working on various fronts, including nutritional intervention, support groups for the patients, or modifying occupation therapy programs. Such measures are necessary to increase the effectiveness of ataxia treatment and improve the quality of life of patients.

摘要

共济失调是一种神经系统疾病,主要症状是行动不稳,在非洲大陆尤其普遍。尽管如此,据推测仍有大量共济失调病例未被确诊,这与提供基因检测的医疗保健机构极少有关。这种疾病最常与多种神经系统疾病相关,包括中风和脑损伤,导致肢体无法控制地移动。然而,在非洲,共济失调增加的主要原因是传染病和干旱导致的食物短缺。在我们的文章中,我们根据共济失调的流行病学分析了不同类型,并描述了社会因素如何使情况恶化。我们详细介绍了旨在解决这一问题的现有国家战略和计划,特别是增加对基因检测、影像学和脑部研究所需基础设施的资金投入。即便采取了这些措施,流行病学研究仍存在一些需要填补的空白,以帮助准确诊断。还必须提高患者教育和医护人员对该问题的认识。我们主张在多个方面开展工作,包括营养干预、患者支持小组或调整职业治疗方案。这些措施对于提高共济失调治疗的有效性和改善患者生活质量是必要 的。