Bueno Cristian Orlando Porras, España Jesús Andrés Beltrán, Guzmán Carolina Murgueitio, Diaz-Brochero Cándida, Peña Ángel Alberto García
Department of Internal Medicine, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, Bogotá, Colombia.
Clin Cardiol. 2025 May;48(5):e70146. doi: 10.1002/clc.70146.
Social determinants of health (SDH) significantly influence cardiovascular outcomes; however, their role in achieving lipid profile goals in older adults remains underexplored. This study aimed to evaluate the association between SDH and nonachievement of LDL cholesterol (LDL-C) and non-HDL cholesterol (non-HDL-C) targets in Colombian adults aged ≥ 60 years.
A cross-sectional analysis was conducted using data from 1270 participants in the SABE Colombia 2015 study. Logistic regression was applied to estimate odds ratios (ORs) for not achieving LDL-C and non-HDL-C goals on the basis of the Framingham, ASCVD 2013, and SCORE2 models.
Non achieving LDL-C goals were associated with female sex, lack of affiliation with the health system and physical inactivity. Physical inactivity was associated with noncompliance on non-HDL-C goals, among others.
SDH are strongly associated with poor lipid control. Addressing modifiable SDHs could enhance cardiovascular risk management in older adults.
健康的社会决定因素（SDH）对心血管疾病结局有显著影响；然而，它们在老年人群实现血脂目标方面的作用仍未得到充分研究。本研究旨在评估SDH与哥伦比亚60岁及以上成年人低密度脂蛋白胆固醇（LDL-C）和非高密度脂蛋白胆固醇（非HDL-C）目标未达成之间的关联。
使用2015年哥伦比亚SABE研究中1270名参与者的数据进行横断面分析。基于弗雷明汉模型、2013年动脉粥样硬化性心血管疾病（ASCVD）模型和SCORE2模型，应用逻辑回归来估计未达成LDL-C和非HDL-C目标的比值比（OR）。
未达成LDL-C目标与女性、未加入医疗体系以及缺乏身体活动有关。缺乏身体活动与未达成非HDL-C目标等情况有关。
SDH与血脂控制不佳密切相关。解决可改变的SDH因素可加强老年人群的心血管风险管理。
