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青少年中处方止痛药滥用与是否使用海洛因的情况:与常规医疗保健、家庭支持、学业成绩、暴力及其他危险行为的关系

Prescription Pain Medication Misuse with and Without Heroin Use Among Adolescents: relationships with Routine Healthcare, Family Support, Academic Performance, Violence, and Other Risky Behaviors.

作者信息

Jalilian-Khave Laya, Stefanovics Elina A, Zhai Zu Wei, Potenza Marc N

机构信息

Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.

Department of Veterans Affairs, New England Mental Illness Research and Education Clinical Center (MIRECC), Connecticut, USA.

出版信息

Subst Use Misuse. 2025;60(9):1400-1410. doi: 10.1080/10826084.2025.2499945. Epub 2025 May 18.

Abstract

BACKGROUND

Opioid misuse is a public health crisis in the United States and globally, impacting adolescents. Prescription pain medication misuse (PPMM) may promote transitioning to heroin use (HU). Understanding relationships between types of opioid misuse (PPMM with and without HU) and seemingly positive (e.g., routine healthcare participation, family support, academic performance) and negative (e.g., violent and other risky behaviors) measures can help address these concerns.

OBJECTIVES

The current study explored PPMM and HU in high-school students, focusing on factors such as routine healthcare participation, family support, and academic performance, and violent and risky behaviors.

METHODS

Using the Youth Risk Behavior Survey data, we compared adolescents misusing prescription pain medications with and without HU and those without either, using chi-square analyses and adjusted odds ratios to understand their relationships with positive and negative measures.

RESULTS

Of 1931 high-school respondents, 180 (8.8%) reported PPMM without HU (PPMM+), 28 (1.4%) reported HU with PPMM (PPMM/HU+), and 1723 (89.80%) reported no PPMM or HU (PPMM-). Adjusted models showed PPMM+ adolescents had lower odds of strong family support and higher odds of specific violent and risky behaviors compared to PPMM-. PPMM/HU+ versus PPMM+ respondents showed lower odds of healthcare participation, family support, and academic performance, and higher odds of specific violent and risky behaviors. Differences were particularly robust between PPMM/HU+ and PPMM- adolescents.

CONCLUSION

Findings suggest PPMM+ and PPMM/HU+ correlate with negative health and functioning in adolescents. Addressing HU requires focusing on specific measures including healthcare utilization, academic performance, and risky behaviors.

摘要

背景

阿片类药物滥用在美国乃至全球都是一场公共卫生危机,影响着青少年。处方止痛药滥用(PPMM)可能促使青少年转向使用海洛因(HU)。了解不同类型的阿片类药物滥用(有或没有使用海洛因的PPMM)与看似积极的因素(如常规医疗保健参与、家庭支持、学业成绩)和消极因素(如暴力及其他危险行为)之间的关系,有助于解决这些问题。

目的

本研究探讨高中生中的PPMM和HU情况,重点关注常规医疗保健参与、家庭支持、学业成绩以及暴力和危险行为等因素。

方法

利用青少年风险行为调查数据,我们对滥用处方止痛药且有或没有使用海洛因的青少年以及两者均未滥用的青少年进行了比较,采用卡方分析和调整后的优势比来了解他们与积极和消极因素之间的关系。

结果

在1931名高中受访者中,180人(8.8%)报告有未使用海洛因的PPMM(PPMM+),28人(1.4%)报告有使用海洛因的PPMM(PPMM/HU+),1723人(89.80%)报告既没有PPMM也没有HU(PPMM-)。调整后的模型显示,与PPMM-的青少年相比,PPMM+的青少年获得强大家庭支持的几率较低,而出现特定暴力和危险行为的几率较高。与PPMM+的受访者相比,PPMM/HU+的受访者在医疗保健参与、家庭支持和学业成绩方面的几率较低,而出现特定暴力和危险行为的几率较高。PPMM/HU+和PPMM-的青少年之间的差异尤为显著。

结论

研究结果表明,PPMM+和PPMM/HU+与青少年的负面健康状况和功能相关。解决海洛因使用问题需要关注包括医疗保健利用、学业成绩和危险行为在内的具体措施。

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