Qi Yanwen, Sun Cheng, Zhou Yang, Luo Lizhou, Wang Chengyuan
Department of Plastic Surgery, China-Japan Friendship Hospital Beijing 100029, China.
Department of Surgical Anesthesiology, China-Japan Friendship Hospital Beijing 100029, China.
Am J Transl Res. 2025 Apr 15;17(4):2701-2711. doi: 10.62347/BVZV3932. eCollection 2025.
To evaluate the efficacy of transvaginal erbium laser therapy in the treatment of Vaginal Relaxation Syndrome (VRS) and its effects on key indicators of vaginal health.
This retrospective study analyzed clinical data from women treated for VRS at the China-Japan Friendship Hospital. Participants were divided into two groups: laser therapy (n = 130) and estrogen treatment (n = 112). Demographic characteristics, clinical outcomes, vaginal microenvironment parameters, and sexual function were assessed. Primary outcomes included changes in pelvic floor muscle strength, vaginal atrophy scores, vaginal pH, lactobacilli grades, and sexual satisfaction.
At the three-month follow-up, the laser group showed significant improvement in pelvic floor muscle strength (P = 0.046) and reductions in vaginal atrophy scores (P = 0.035) compared to the estrogen group. Additionally, patients in the laser group reported greater sexual satisfaction, including increased orgasm frequency (P = 0.007). While improvements in lactobacilli grades and vaginal pH were observed in the laser group, these changes were not statistically significant (both P > 0.05). Adverse reactions were mild and occurred less frequently in the erbium laser group (P < 0.05).
Transvaginal erbium laser therapy is an effective intervention for alleviating VRS symptoms and enhancing pelvic floor muscle function. It also contributes to improved sexual satisfaction and supports the maintenance of a healthy vaginal microenvironment.
评估经阴道铒激光治疗阴道松弛综合征(VRS)的疗效及其对阴道健康关键指标的影响。
这项回顾性研究分析了中日友好医院接受VRS治疗的女性的临床数据。参与者分为两组:激光治疗组(n = 130)和雌激素治疗组(n = 112)。评估了人口统计学特征、临床结局、阴道微环境参数和性功能。主要结局包括盆底肌肉力量、阴道萎缩评分、阴道pH值、乳酸杆菌等级和性满意度的变化。
在三个月的随访中,与雌激素组相比,激光组的盆底肌肉力量有显著改善(P = 0.046),阴道萎缩评分降低(P = 0.035)。此外,激光组的患者报告了更高的性满意度,包括性高潮频率增加(P = 0.007)。虽然激光组的乳酸杆菌等级和阴道pH值有所改善,但这些变化无统计学意义(P均> 0.05)。铒激光组的不良反应较轻,发生率较低(P < 0.05)。
经阴道铒激光治疗是缓解VRS症状和增强盆底肌肉功能的有效干预措施。它还有助于提高性满意度,并有助于维持健康的阴道微环境。