Suppr超能文献

你的肾脏还好吗?早检测,保护肾脏健康。

Are your kidneys ok? Detect early to protect kidney health.

作者信息

Vassalotti Joseph A, Francis Anna, Soares Dos Santos Augusto Cesar, Correa-Rotter Ricardo, Abdellatif Dina, Hsiao Li-Li, Roumeliotis Stefanos, Haris Agnes, Kumaraswami Latha A, Lui Siu-Fai, Balducci Alessandro, Liakopoulos Vassilios

机构信息

Department of Medicine-Renal Medicine, Mount Sinai Hospital, New York, NY, USA.

Department of Nephrology, Queensland Children's Hospital, Queensland, Australia.

出版信息

Ren Fail. 2025 Dec;47(1):2503514. doi: 10.1080/0886022X.2025.2503514. Epub 2025 May 20.

Abstract

Early identification of kidney disease can protect kidney health, prevent kidney disease progression and related complications, reduce cardiovascular disease risk and decrease mortality. We must ask "?" using serum creatinine to estimate kidney function and urine albumin to assess for kidney and endothelial damage. Evaluation for causes and risk factors for chronic kidney disease (CKD) includes testing for diabetes and measurement of blood pressure and body mass index. This World Kidney Day we assert that case-finding in high-risk populations, or even population level screening, can decrease the burden of kidney disease globally. Early-stage CKD is asymptomatic, simple to test for and recent paradigm shifting CKD treatments such as sodium glucose co-transporter-2 inhibitors dramatically improve outcomes and favor the cost-benefit analysis for screening or case-finding programs. Despite this, numerous barriers exist, including resource allocation, healthcare funding, healthcare infrastructure and healthcare-professional and population awareness of kidney disease. Coordinated efforts by major kidney non-governmental organizations to prioritize the kidney health agenda for governments and aligning early detection efforts with other current programs will maximize efficiencies.

摘要

早期识别肾脏疾病可以保护肾脏健康,预防肾脏疾病进展及相关并发症,降低心血管疾病风险并减少死亡率。我们必须对使用血清肌酐来估计肾功能以及使用尿白蛋白来评估肾脏和内皮损伤提出质疑。对慢性肾脏病(CKD)病因和危险因素的评估包括糖尿病检测、血压测量和体重指数测量。在今年的世界肾脏日,我们断言,在高危人群中进行病例发现,甚至在人群层面进行筛查,可以减轻全球肾脏疾病的负担。早期CKD没有症状,检测简单,并且近期诸如钠-葡萄糖协同转运蛋白2抑制剂等改变CKD治疗模式的药物显著改善了治疗效果,有利于筛查或病例发现项目的成本效益分析。尽管如此,仍然存在许多障碍,包括资源分配、医疗保健资金、医疗保健基础设施以及医疗专业人员和公众对肾脏疾病的认识。主要肾脏非政府组织应协同努力,为各国政府将肾脏健康议程列为优先事项,并使早期检测工作与其他现有项目保持一致,从而实现效率最大化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2a1/12096682/0a103fa66692/IRNF_A_2503514_F0001_C.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验