Shanehsazzadeh Faezeh, DeLancey John O L, Ashton-Miller James A
Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Department of Obstetrics & Gynecology, University of Michigan, Ann Arbor, MI 48109, USA.
Biosensors (Basel). 2025 May 11;15(5):306. doi: 10.3390/bios15050306.
Urinary incontinence affects many women, yet there are no monitoring devices capable of accurately capturing flow dynamics during everyday activities. Building on our initial development of a wearable personal uroflowmeter, this study enhances the device's performance under realistic, dynamic conditions similar to those encountered in daily living. We integrated an optimized eight-vane Etoile flow conditioner with a 0.2D opening into the device. Both computational fluid dynamics simulations and experimental tests demonstrated that this flow conditioner significantly reduced turbulence intensity by 82% and stabilized the axial velocity profile by 67%, increasing the R of flow rate measurements from 0.44 to 0.92. Furthermore, our machine learning framework-utilizing a support vector machine (SVM) and an extreme gradient boosting (XGBoost) model with principal component analysis (PCA)-accurately predicted the true flow rate with high correlations, robust performance, and minimal overfitting. For the test dataset, the SVM achieved a correlation of 0.86, an R of 0.74, and an MAE of 2.8, whereas the XGBoost-PCA model exhibited slightly stronger performance, with a correlation of 0.88, an R of 0.76, and an MAE of 2.6. These advances established a solid foundation for developing a reliable, wearable uroflowmeter capable of effectively monitoring urinary incontinence in real-world settings.
尿失禁影响着许多女性,但目前尚无能够在日常活动中准确捕捉尿液流动动力学的监测设备。基于我们最初开发的可穿戴式个人尿流计,本研究在类似于日常生活中遇到的现实动态条件下提升了该设备的性能。我们将一个优化的八叶片埃托雷(Etoile)流动调节器与一个0.2D开口集成到该设备中。计算流体动力学模拟和实验测试均表明,这种流动调节器显著降低了82%的湍流强度,并使轴向速度分布稳定了67%,将流速测量的相关系数R从0.44提高到了0.92。此外,我们的机器学习框架——利用支持向量机(SVM)和带有主成分分析(PCA)的极端梯度提升(XGBoost)模型——以高相关性、稳健性能和最小的过拟合准确预测了真实流速。对于测试数据集,SVM的相关系数为0.86,R为0.74,平均绝对误差(MAE)为2.8,而XGBoost - PCA模型表现略强,相关系数为0.88,R为0.76,MAE为2.6。这些进展为开发一种能够在现实环境中有效监测尿失禁的可靠可穿戴尿流计奠定了坚实基础。