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西班牙北部孕妇膳食中食品污染物的暴露情况及其对胎儿人体测量参数的潜在影响。

Dietary Exposure to Food Contaminants of Pregnant Women in Northern Spain and Possible Effects on Fetal Anthropometric Parameters.

作者信息

Hinojosa-Nogueira Daniel, Bahamonde José Ramón, Aguilera-Nieto Marta, Navajas-Porras Beatriz, González-Vigil Verónica, Rufián-Henares José Ángel, Pastoriza de la Cueva Silvia

机构信息

Unidad de Gestión Clínica de Endocrinología y Nutrición, Laboratorio del Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Universitario de Málaga (Virgen de la Victoria), 29590 Málaga, Spain.

Facultad Padre Ossó, Clínica Universitaria INYPEMA, Universidad de Oviedo, 33008 Oviedo, Spain.

出版信息

Toxics. 2025 May 16;13(5):399. doi: 10.3390/toxics13050399.

Abstract

A considerable number of organizations are working to improve food safety, with particular attention to vulnerable groups such as pregnant women due to the important influence of diet on fetal development. The aim of this study was to evaluate exposure to 11 food processing contaminants and their effects on maternal and fetal health. Online questionnaires during the first and third trimesters were used to analyze the intake and exposure to different food contaminants, estimated from the contaminants food database "CONT11", in 84 pregnant women in Oviedo (Spain) and their influence on newborn anthropometric data. Exposure to certain contaminants, such as acrylamide or total polycyclic aromatic hydrocarbons, was found to have a significant impact on maternal and fetal health, particularly in relation to birth weight or head circumference. During the third trimester, pregnant women reported dietary improvement and reduced exposure to dietary contaminants. Identifying the foods and food groups that contribute most to exposure and the potential for health professionals will facilitate the development of basic exposure reduction strategies. This study is one of the few to assess the exposure of pregnant women to a wide range of contaminants and their impact on fetal health, providing a baseline for future research.

摘要

相当多的组织致力于改善食品安全,尤其关注孕妇等弱势群体,因为饮食对胎儿发育有重要影响。本研究的目的是评估11种食品加工污染物的暴露情况及其对母婴健康的影响。通过在孕早期和孕晚期使用在线问卷,分析了西班牙奥维耶多84名孕妇从污染物食品数据库“CONT11”估算出的不同食品污染物的摄入量和暴露情况,以及它们对新生儿人体测量数据的影响。研究发现,接触某些污染物,如丙烯酰胺或总多环芳烃,对母婴健康有显著影响,尤其是对出生体重或头围。在孕晚期,孕妇报告饮食有所改善,饮食污染物暴露减少。确定对暴露贡献最大的食物和食物类别以及卫生专业人员的潜在作用,将有助于制定基本的减少暴露策略。本研究是少数评估孕妇接触多种污染物及其对胎儿健康影响的研究之一,为未来研究提供了基线。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e623/12116101/df54ee320c97/toxics-13-00399-g001.jpg

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