Wang Ju, Cheng Yamei, Yan Qiqi, Li Dandan, Wang Ruifeng, Liu Guiling
Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China.
BMC Nephrol. 2025 May 28;26(1):264. doi: 10.1186/s12882-024-03884-5.
Acremonium sclerotigenum exhibits antagonistic properties against various detrimental organisms, including bacteria, nematodes, and mites. As the predominant species within the Acremonium genus, it is characterized as an opportunistic pathogenic fungus that commonly inhabits soil and plants as a saprotroph. Additionally, it has been identified as the etiological agent of superficial infections, such as onychomycosis, and, less frequently, invasive infections.
This study presents a unique case involving a 79-year-old male who developed peritoneal dialysis-associated peritonitis (PDAP) attributed to Acremonium sclerotigenum. To the best of our knowledge, this represents the first documented instance of PDAP caused by this fungal species.
The identification of pathogens is essential for diagnosing PDAP.
硬皮顶孢霉对包括细菌、线虫和螨虫在内的多种有害生物具有拮抗特性。作为顶孢霉属中的主要物种,它被归类为机会致病性真菌,通常以腐生菌的形式存在于土壤和植物中。此外,它已被确定为浅表感染(如甲癣)的病原体,较少情况下也会引起侵袭性感染。
本研究呈现了一个独特病例,一名79岁男性因硬皮顶孢霉引发了腹膜透析相关腹膜炎(PDAP)。据我们所知,这是该真菌物种导致PDAP的首例有记录病例。
病原体鉴定对于诊断PDAP至关重要。