中国儿童人群血浆氨基酸的年龄特异性参考区间及其与营养摄入的关联。

Age-specific reference intervals for plasma amino acids and their associations with nutrient intake in the Chinese pediatric population.

作者信息

Wen Yang, Liu Qing, Zeng Hongbo, Lyu Lina, He Xuezhen, Zhang Xin, Lyu Wentao, Chen Weijun, Xiao Yingping

机构信息

State Key Laboratory for Quality and Safety of Agro-Products, Institute of Agro-Product Safety and Nutrition Zhejiang Academy of Agricultural Sciences Hangzhou China.

College of Biotechnology and Bioengineering Zhejiang University of Technology Hangzhou China.

出版信息

Imeta. 2025 May 29;4(3):e70051. doi: 10.1002/imt2.70051. eCollection 2025 Jun.

DOI:10.1002/imt2.70051

PMID:40469518

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12130562/

Abstract

A total of 2901 healthy Chinese children aged 0-12 years were enrolled in the reference group; 102 confirmed Phenylketonuria cases were included as validation individuals. Establishing the age-specific reference intervals of 42 plasma amino acids in Chinese pediatric populations. Profiling dynamic interactions between multiple nutrient intake and amino acid change patterns.

摘要

共纳入2901名0至12岁的健康中国儿童作为参考组；102例确诊的苯丙酮尿症病例作为验证个体。建立中国儿科人群42种血浆氨基酸的年龄特异性参考区间。剖析多种营养素摄入与氨基酸变化模式之间的动态相互作用。