Lyons Hannah E, Peel Andrew, Gonzalez Macarena, Deluao Josh, Olatunji Oluwabunmi, Nikitaras Victoria, McPherson Nicole O
Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia.
Freemasons Centre for Male Health and Wellbeing, The University of Adelaide, Adelaide, South Australia, Australia.
Nat Rev Urol. 2025 Jun 6. doi: 10.1038/s41585-025-01047-1.
Declining fertility, overlooked mental health, and reduced life expectancy underscore the urgent need for renewed attention to men's health. A semen analysis, traditionally used to assess fertility, holds untapped potential as a tool for promoting lifestyle changes and preventing chronic diseases in men. Spermatogenesis is highly sensitive to environmental and lifestyle factors and can be an early indicator of overall health. Disruptions in this process can signal underlying systemic issues and predict long-term health risks, including cardiovascular disease and metabolic disorders. An increasing number of men seek to engage in preconception care, as fertility is closely tied to a man's sense of masculinity, identity and aspirations for fatherhood. In this context, a semen analysis can be a powerful motivator to encourage healthy behaviours and proactive health management. By incorporating semen analysis into primary care, health care providers can leverage men's desire for fatherhood as an entry point to discuss broader health concerns, such as mental well-being, nutrition and physical activity. This approach would address immediate reproductive health, and also promote long-term wellness, helping to reduce the burden of chronic disease in men.
生育能力下降、心理健康被忽视以及预期寿命缩短，凸显了重新关注男性健康的迫切需求。传统上用于评估生育能力的精液分析，作为促进男性生活方式改变和预防慢性病的工具，具有尚未开发的潜力。精子发生对环境和生活方式因素高度敏感，并且可以作为整体健康的早期指标。这一过程的中断可能预示着潜在的系统性问题，并预测包括心血管疾病和代谢紊乱在内的长期健康风险。越来越多的男性寻求孕前保健，因为生育能力与男性的男子气概、身份认同以及为人父的愿望密切相关。在这种背景下，精液分析可以成为鼓励健康行为和积极健康管理的有力动力。通过将精液分析纳入初级保健，医疗保健提供者可以利用男性为人父的愿望作为切入点，讨论更广泛的健康问题，如心理健康、营养和体育活动。这种方法将解决直接的生殖健康问题，同时促进长期健康，有助于减轻男性慢性病的负担。
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