Daubert J C, Deplace C, Bourdonnec C, Pony J C, Gouffault J
Arch Mal Coeur Vaiss. 1977 Mar;70(3):243-55.
70 patients with acute myocardial infarction were submitted to a full haemodynamic assessment at the onset of the condition. In 28 of them there was a disproportionate rise in the right ventricular end-diastolic pressure which could not be explained on the basis of a primary rise in left ventricular filling pressures; these were divisable into two subgroups: -- 19 infarcts without septal rupture, almost all with an inferiorly or posteriorly placed lesion (17); in these cases, an analysis of the curves shows, among other features, a syndrome of adiastole whose three forms (minor, moderate or severe) correlate well with the clinical features. Six cases died, and in four of those it was possible to study the correlation with the post-mortem findings: there were major lesions of the free wall of the right ventricle in 3 cases, but constrictive pericardial changes, the main differential diagnosis of right ventricular infarction, in the fourth. -- 9 cases of necrosis of the septum with rupture, of which only 3 had a syndrome of adiastole; three of these necroses were posterior, and post-mortem examination in two of them confirmed that there were indeed major lesions in the posterior wall of the right ventricle. It therefore seems that the diagnosis of infarction of the right ventricle is a haemodynamic one, and rests especially on the discovery of a syndrome of adiastole. Findings such as these are confined almost exclusively to posteriorly placed infarctions.
70例急性心肌梗死患者在发病时接受了全面的血流动力学评估。其中28例患者右心室舒张末期压力不成比例升高,无法用左心室充盈压原发性升高来解释;这些患者可分为两个亚组:——19例无室间隔破裂的梗死患者,几乎所有患者梗死灶位于下壁或后壁(17例);在这些病例中,对曲线的分析显示,除其他特征外,存在舒张期综合征,其三种形式(轻度、中度或重度)与临床特征密切相关。6例患者死亡,其中4例患者能够研究与尸检结果的相关性:3例患者右心室游离壁有严重病变,但第4例患者存在缩窄性心包改变,这是右心室梗死的主要鉴别诊断。——9例室间隔坏死伴破裂患者,其中只有3例有舒张期综合征;其中3例坏死位于后壁,其中2例尸检证实右心室后壁确实存在严重病变。因此,右心室梗死的诊断似乎是基于血流动力学的,尤其依赖于舒张期综合征的发现。此类发现几乎仅局限于后壁梗死。