Shukla Ankit, Kalayarasan Raja, Sai Krishna Pothugunta, Pottakkat Biju
Department of Surgery, Dr Rajendra Prasad Government Medical College, Tanda 176001, India.
Department of Surgical Gastroenterology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry 605006, India.
World J Clin Oncol. 2025 May 24;16(5):107039. doi: 10.5306/wjco.v16.i5.107039.
Pancreatic carcinoma is one of the most lethal malignancies and has a dismal prognosis. However, advances in diagnostic modalities and better multidisciplinary management have contributed to improved survival in these patients. Of late, various recurrence patterns have been observed; the most common of them being distant metastasis followed by the pancreatic bed and lymph node recurrence. Recurrence in the remnant pancreas is on the rise due to improved survival in patients who previously underwent surgery for pancreatic cancer. Total remnant pancreatectomy is an appealing option in resectable remnant pancreatic carcinoma without distant metastasis. It is an entity showing an increasing incidence and demanding further in-depth studies to elucidate the exact pathological mechanism and to establish appropriate management protocols.
胰腺癌是最致命的恶性肿瘤之一,预后很差。然而,诊断方式的进步和更好的多学科管理有助于提高这些患者的生存率。最近,观察到了各种复发模式;其中最常见的是远处转移,其次是胰床和淋巴结复发。由于先前接受过胰腺癌手术的患者生存率提高,残余胰腺的复发率正在上升。对于无远处转移的可切除残余胰腺癌,全胰切除术是一种有吸引力的选择。这是一种发病率不断上升的疾病,需要进一步深入研究以阐明确切的病理机制并制定适当的管理方案。