Mukundan Arvind, Gupta Devansh, Karmakar Riya, Wang Hsiang-Chen
Department of Chemistry, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 602105, Tamil Nādu, India.
Department of Mechanical Engineering, Center for Innovative Research on Aging Society (CIRAS), National Chung Cheng University, Chiayi 621, Taiwan.
World J Gastrointest Endosc. 2025 Jun 16;17(6):107088. doi: 10.4253/wjge.v17.i6.107088.
In this letter, a commentary on the article by Xu has been provided. Gastrointestinal stomal tumours (GISTs) are rare tumours that originate commonly in stomach (60%-70%) and small intestine (30%-40%). The course of treatment especially oesophageal GIST is very complex and hard to diagnose because of limited availability of pathological and clinical data. Endoscopic resection (ER) is a minimally invasive approach for removing tumours from the oesophagus and digestive system that does not require open surgery and is especially successful for very small and low-risk GIST. A retrospective examination of 32 patients treated with ER between 2012 and 2023 was conducted to analyse clinical and pathological characteristics, effectiveness of therapy, and long-term prognosis. The findings demonstrate resection was achieved in 96.9% of cases with an R0 resection rate of 75% with a median size of tumour was approximately 2.12 cm. Post-surgery complication like hydrothorax, post-endoscopic submucosal dissection electrocoagulation syndrome occurred in about 25% of cases which later go resolved by conservative treatment. Recurrence of GIST was approximately 9.4% primarily in high-risk cases. ER should be widely adopted in clinical practise preferably for managing low-risk oesophageal GIST because of its high success rate, low recurrence rates and excellent survival results, ensuring better patient prognosis.
在这封信中,对徐的文章进行了评论。胃肠道间质瘤(GISTs)是罕见肿瘤,通常起源于胃(60%-70%)和小肠(30%-40%)。由于病理和临床数据有限,治疗过程尤其是食管GIST非常复杂且难以诊断。内镜切除术(ER)是一种从食管和消化系统切除肿瘤的微创方法,不需要开腹手术,对于非常小的低风险GIST尤其成功。对2012年至2023年间接受ER治疗的32例患者进行回顾性检查,以分析临床和病理特征、治疗效果及长期预后。结果显示,96.9%的病例实现了切除,R0切除率为75%,肿瘤中位大小约为2.12厘米。约25%的病例出现了如胸腔积液、内镜下黏膜下剥离电凝综合征等术后并发症,这些并发症后来通过保守治疗得到解决。GIST的复发率约为9.4%,主要发生在高风险病例中。由于ER成功率高、复发率低且生存结果良好,能确保更好的患者预后,因此应在临床实践中广泛采用,尤其适用于治疗低风险食管GIST。