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卡塔尔基层医疗环境中抗高血压药物的处方趋势和模式:一项回顾性观察研究。

Prescribing trends and patterns for antihypertensive agents in primary healthcare settings in Qatar: a retrospective observational study.

作者信息

Abdelkader Nada Nabil, Awaisu Ahmed, Elewa Hazem, Mahfoud Ziyad, Al Abdulla Samya Ahmad, Owais Amjad, El Hajj Maguy Saffouh

机构信息

Clinical Pharmacy and Practice Department, College of Pharmacy, QU Health, Qatar University, Doha, Qatar.

Biostatistics and Healthcare Policy and Research, Weill Cornell Medicine, Qatar Foundation, Doha, Qatar.

出版信息

J Pharm Policy Pract. 2025 Jun 18;18(1):2512183. doi: 10.1080/20523211.2025.2512183. eCollection 2025.

Abstract

BACKGROUND

An observational retrospective study was conducted in the primary care setting in Qatar to evaluate the prescribing trends and patterns of antihypertensives in hypertensive patients.

METHODS

Included patients were adult patients (aged ≥18 years) diagnosed with essential hypertension and attending Primary Health Care Corporation (PHCC) clinics in Qatar between January 2017 and March 2021. A sample of 2185 patients was randomly selected. The data were collected from PHCC's electronic medical records system, Cerner©.

RESULTS

Angiotensin Converting Enzyme inhibitors (ACEIs) prescriptions decreased from 38% in 2017 to 21% in 2021, and that of Angiotensin Receptor Blockers (ARBs) from 37% in 2017 to 31% in 2021. Patients with prescribed Calcium Channel Blockers (CCBs) increased from 31% in 2017 to 40% in 2021. The prescribing of thiazide diuretics declined from 32% in 2017 to 9% in 2021. In 2017, the most prescribed antihypertensive class was ACEIs (38%), while the least prescribed antihypertensive class was loop diuretics (1.4%). In 2018, the most prescribed class of antihypertensives was CCBs (36%) and the least prescribed was vasodilators (0.1%). In 2019, 2020 and 2021, CCBs were the most prescribed.

CONCLUSION

These findings are consistent with national and international guidelines for hypertension management and with published literature. Yet, there is still room for improvement to optimise antihypertensive prescribing practices. Prescribers need to address potential gaps and explore ways to enhance their hypertension management, so that patients have access to effective and evidence-based treatments.

摘要

背景

在卡塔尔的基层医疗环境中开展了一项观察性回顾性研究,以评估高血压患者的抗高血压药物处方趋势和模式。

方法

纳入的患者为2017年1月至2021年3月期间在卡塔尔被诊断为原发性高血压并在初级卫生保健公司(PHCC)诊所就诊的成年患者(年龄≥18岁)。随机抽取了2185名患者作为样本。数据从PHCC的电子病历系统Cerner©中收集。

结果

血管紧张素转换酶抑制剂(ACEI)的处方比例从2017年的38%降至2021年的21%,血管紧张素受体阻滞剂(ARB)的处方比例从2017年的37%降至2021年的31%。使用钙通道阻滞剂(CCB)的患者比例从2017年的31%增至2021年的40%。噻嗪类利尿剂的处方比例从2017年的32%降至2021年的9%。2017年,处方量最多的抗高血压药物类别是ACEI(38%),而处方量最少的是襻利尿剂(1.4%)。2018年,处方量最多的抗高血压药物类别是CCB(36%),最少的是血管扩张剂(0.1%)。2019年、2020年和2021年,CCB的处方量最多。

结论

这些发现与高血压管理的国家和国际指南以及已发表的文献一致。然而,优化抗高血压药物处方实践仍有改进空间。处方者需要解决潜在差距并探索加强高血压管理的方法,以便患者能够获得有效且基于证据的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7327/12180352/2f2548232b3c/JPPP_A_2512183_F0001_OC.jpg

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