锂治疗引起的痤疮样皮疹可能与螨类（前气门亚目：蠕形螨科）有关：一种假说。
Acneiform Eruptions Caused by Lithium Treatment May Be Related to Mites (Prostigmata: Demodecidae): A Hypothesis.
作者信息
El-Mallakh Rif S, Doroodgar Masoud, Pahwa Mehak, Elsayed Omar H A
机构信息
Mood Disorders Research Program, Depression Center, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA.
出版信息
Biology (Basel). 2025 May 25;14(6):605. doi: 10.3390/biology14060605.
Acneiform eruptions are a common adverse effect of lithium treatment that may impact adherence. It is not clear why lithium may worsen these lesions and treatment has focused on traditional treatments for acne. mites are known to commensurably exist in a large fraction of humans and are known to cause dermatologic conditions in a minority of individuals. An association with acneiform eruptions is well documented but is generally believed to not be causative. We present a hypothesis that lithium treatment may alter the environment of mites in a fashion that may increase their propensity to cause disease. If that is accurate, treatment with acaricidal agents may be an additional option.
痤疮样皮疹是锂盐治疗常见的不良反应，可能影响治疗依从性。目前尚不清楚锂盐为何会使这些皮疹恶化，治疗主要集中在痤疮的传统治疗方法上。已知大量人群中存在螨虫，少数个体中螨虫会引发皮肤病。螨虫与痤疮样皮疹的关联已有充分记录，但一般认为螨虫并非其病因。我们提出一个假说，即锂盐治疗可能以某种方式改变螨虫生存环境，从而增加其致病倾向。如果这一假说正确，使用杀螨剂治疗可能是一种额外的选择。
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