Noufal Yazan, Richter Marcus, Hartung Philipp, Schmitz Felix, Fröhlich Matthias, Drees Philipp, Afghanyar Yama, Naisan Martin
Spine Center, St. Josefs Hospital Wiesbaden, 65189 Wiesbaden, Germany.
Department of Orthopaedic Surgery, Trauma Surgery and Sports Traumatology, University of Witten/Herdecke, Cologne-Merheim Medical Centre (CMMC), 51109 Cologne, Germany.
J Clin Med. 2025 Jun 17;14(12):4319. doi: 10.3390/jcm14124319.
Cervical spondylotic myelopathy (CSM) is a progressive neurological disorder caused by spinal cord compression in the cervical spine. The Japanese Orthopaedic Association (JOA) score is commonly used to quantify neurological impairment. Surgical decompression is the main treatment, aiming to relieve pressure on the spinal cord and improve neurological function. Historically, the primary goal was to halt disease progression; however, recent studies suggest an improvement even in cases with mild symptoms. The extent to which the shifting of the spinal cord contributes to clinical improvement remains controversial. This study included 95 patients who underwent dorsal decompression and instrumentation for cervical myelopathy between 2020-2024. Patients were followed up at 3 and 12 months post surgery. Dorsal decompression resulted in a significant improvement in neurological function as measured by the JOA score at three months and one-year post-operation (0.0004 and 0.006, respectively). The average posterior spinal cord shift (PSS) was 3 mm. The prevalence of C5-palsy was 3.1%. Linear and logistic multivariable regression showed no significant relationship between PSS and JOA score alteration or subjective clinical improvement, but a multivariable regression analysis identified the ASA score as a significant negative predictor of neurological improvement. Dorsal decompression in CSM is a safe procedure concerning neurological complications and does not only stop the worsening of symptoms but indeed improves the JOA score and the subjective clinical situation. Although PSS was observed postoperatively, the extent of PSS showed no statistically significant relationship with JOA score improvement.
脊髓型颈椎病(CSM)是一种由颈椎脊髓受压引起的进行性神经疾病。日本骨科协会(JOA)评分常用于量化神经功能损害。手术减压是主要治疗方法,旨在减轻脊髓压力并改善神经功能。从历史上看,主要目标是阻止疾病进展;然而,最近的研究表明,即使在症状较轻的病例中也有改善。脊髓移位对临床改善的贡献程度仍存在争议。本研究纳入了95例在2020年至2024年间接受颈椎脊髓病后路减压及内固定术的患者。术后分别在3个月和12个月进行随访。后路减压术后3个月和1年时,通过JOA评分测量,神经功能有显著改善(分别为0.0004和0.006)。脊髓平均后移(PSS)为3mm。C5麻痹的发生率为3.1%。线性和逻辑多变量回归显示,PSS与JOA评分改变或主观临床改善之间无显著关系,但多变量回归分析确定ASA评分是神经功能改善的显著负性预测因素。CSM的后路减压在神经并发症方面是一种安全的手术,不仅能阻止症状恶化,而且确实能改善JOA评分和主观临床状况。虽然术后观察到了PSS,但PSS的程度与JOA评分改善无统计学显著关系。