Clark Haley, Venishetty Nikit, Howell Skyler, Deebel Nicholas A, Muthigi Akhil
School of Engineering Medicine, Texas A&M University, Houston, TX, USA.
Paul L. Foster School of Medicine, Texas Tech Health Sciences Center El Paso, El Paso, TX, USA.
Int J Impot Res. 2025 Jun 27. doi: 10.1038/s41443-025-01112-8.
Artificial intelligence (AI) is reshaping the landscape of men's health by enhancing diagnostic accuracy, personalizing treatment strategies, and improving clinical efficiency. This narrative review explores the applications and ethical considerations of AI technologies, including machine learning, deep learning, and natural language processing, in key areas of men's health such as fertility, erectile dysfunction, Peyronie's disease, testosterone deficiency, and premature ejaculation. In reproductive medicine AI improves sperm morphology assessment, embryo selection, and prediction of seminal quality, offering more objective and accurate alternatives to traditional methods. For erectile dysfunction, AI supports diagnosis through advanced imaging, wearable sensors, and predictive modeling, while also contributing to drug discovery. In the context of Peyronie's disease, AI enhances curvature assessment and three-dimensional modeling, improving diagnostic precision and surgical planning. AI also holds promise in improving the evaluation of testosterone deficiency by optimizing symptom questionnaires. Furthermore, AI-powered chatbots are emerging as accessible tools for patient education across various men's health topics, including pre-consultation support for conditions such as premature ejaculation and vasectomy counseling. Despite AI's advancements in men's health, challenges remain in ensuring ethical implementation, protecting data privacy, patient autonomy, and promoting algorithm transparency. This review highlights the transformative potential of AI in the future of men's health while emphasizing the importance of responsible integration guided by clinical validation, regulatory oversight, and adherence to ethical principles.
人工智能(AI)正在重塑男性健康领域,它提高了诊断准确性,使治疗策略个性化,并提升了临床效率。这篇叙述性综述探讨了人工智能技术,包括机器学习、深度学习和自然语言处理,在男性健康关键领域,如生育、勃起功能障碍、佩罗尼氏病、睾酮缺乏和早泄等方面的应用及伦理考量。在生殖医学中,人工智能改善了精子形态评估、胚胎选择以及精液质量预测,为传统方法提供了更客观、准确的替代方案。对于勃起功能障碍,人工智能通过先进成像、可穿戴传感器和预测模型支持诊断,同时也有助于药物研发。在佩罗尼氏病方面,人工智能增强了弯曲度评估和三维建模,提高了诊断精度和手术规划水平。人工智能在优化症状问卷以改善睾酮缺乏评估方面也具有潜力。此外,由人工智能驱动的聊天机器人正成为跨各种男性健康主题进行患者教育的便捷工具,包括为早泄和输精管结扎咨询等情况提供咨询前支持。尽管人工智能在男性健康领域取得了进展,但在确保道德实施、保护数据隐私、患者自主权以及提高算法透明度方面仍存在挑战。本综述强调了人工智能在男性健康未来的变革潜力,同时强调了在临床验证、监管监督和遵守伦理原则指导下进行负责任整合的重要性。