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加拿大一项基于人群队列研究中,下腔静脉滤器取出的预测因素。

Predictors of inferior vena cava filter retrieval in a population-based Canadian cohort.

作者信息

Ip Serena, Salata Konrad, Luo Jin, de Mestral Charles, Roche-Nagle Graham

机构信息

Faculty of Health Sciences, Queen's University, Kingston, Ontario, Canada.

Division of Vascular Surgery, University of Toronto, Toronto, Ontario, Canada.

出版信息

J Vasc Surg Venous Lymphat Disord. 2025 Jun 26;13(6):102283. doi: 10.1016/j.jvsv.2025.102283.

Abstract

BACKGROUND

The objective of this study was to determine the predictors of inferior vena cava (IVC) filter retrieval in a contemporary North American cohort of patients who received an IVC filter.

METHODS

A retrospective population-based cohort study was conducted using Ontario administrative health data. Physician service fee codes were used to identify all adults with an IVC filter placement from January 1, 2010, to December 31, 2019. The cumulative incidence of filter retrieval over time was calculated, accounting for death as a competing risk. Multivariable sub-distribution hazard regression models were constructed to quantify the association between covariates and the likelihood of filter retrieval.

RESULTS

A total of 5617 people received an IVC filter during the study period. Median follow-up was 1.8 years (interquartile range, 0.2-5.4 years). The probability of filter retrieval plateaued under 40% with most retrievals (96%; n = 2049 of 2135) occurring within 1 year of placement. Filter placement in a teaching hospital (hazard ratio, 1.85; 95% confidence interval, 1.60-2.02), and placement after 2016 were associated with a greater likelihood of filter retrieval. Older age and greater comorbidity were associated with a lower likelihood of filter retrieval.

CONCLUSIONS

In this population-based study of IVC filter retrieval, less than 40% of filters were retrieved, mostly within 1 year of insertion. Better coordination and standardization of services responsible for follow-up of patients with IVC filters are needed.

摘要

背景

本研究的目的是确定当代北美接受下腔静脉(IVC)滤器植入的患者队列中滤器取出的预测因素。

方法

利用安大略省行政卫生数据进行了一项基于人群的回顾性队列研究。使用医师服务费代码识别2010年1月1日至2019年12月31日期间所有植入IVC滤器的成年人。计算随时间推移滤器取出的累积发生率,并将死亡作为竞争风险进行考虑。构建多变量亚分布风险回归模型以量化协变量与滤器取出可能性之间的关联。

结果

在研究期间,共有5617人接受了IVC滤器植入。中位随访时间为1.8年(四分位间距,0.2 - 5.4年)。滤器取出的概率在40%以下趋于平稳,大多数取出(96%;2135例中的2049例)发生在植入后1年内。在教学医院植入滤器(风险比,1.85;95%置信区间,1.60 - 2.02)以及在2016年之后植入与滤器取出的可能性更大相关。年龄较大和合并症较多与滤器取出的可能性较低相关。

结论

在这项基于人群的IVC滤器取出研究中,不到40%的滤器被取出,大多在植入后1年内。需要对负责IVC滤器植入患者随访的服务进行更好的协调和标准化。

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