Issa Tariq Z, Reynolds Christopher A, Dooley Jennings H, Thomas W Christian, Sontag-Milobsky Isaac, Hardt Kevin D, Manning David W
Department of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Department of Orthopaedic Surgery, University of North Carolina, Chapel Hill, NC, USA.
Arthroplast Today. 2025 Jun 13;34:101729. doi: 10.1016/j.artd.2025.101729. eCollection 2025 Aug.
Predictive tools such as the risk assessment and prediction tool (RAPT) and the 5-item modified Frailty Index (mFI-5) have been created to assist in discharge planning after total joint arthroplasty (TJA) including hip and knee arthroplasty, but there is no uniform determination of frailty risks. The primary objective was to compare the modified Frailty Index and RAPT in assessing outcomes following TJA, and we hypothesized similar performance between both measures.
We conducted a retrospective study of patients aged 50 years and more undergoing primary elective TJA at a single academic tertiary center through the same Enhanced Recovery After Surgery protocol. Patients were stratified using mFI-5 and RAPT scores tabulated during preoperative clinic visits. Multivariable analyses were conducted to assess independent associations of mFI-5 and RAPT with complications, prolonged length of stay, readmissions, and nonhome discharge. Youden's index was used to construct receiver operating characteristic curves to assess the predictive ability of mFI-5, Charlson Comorbidity Index, and RAPT in classifying outcomes.
A total 858 TJA patients were included. Overall, 547 (63.8%) were not frail, 273 (31.8%) were prefrail, and 38 (4.4%) were frail. When stratifying by RAPT, 369 (43.0%) had RAPT > 9 (low-risk), 402 (46.9%) had RAPT 6-9 (moderate-risk), and 87 (10.1%) had RAPT < 6 (high-risk). Prefrailty (odds ratio [OR]: 2.31, = .006) and frailty (OR: 8.82, < .001) were associated with higher nonhome discharge. Both RAPT 6-9 (OR: 4.87, = .001) and RAPT < 6 (OR: 27.2, < .001) were associated with nonhome discharge. Neither was independently associated with complications or readmissions. These indices were poor independent predictors of complications, readmissions, and prolonged length of stay (all, area under the curve [AUC] < 0.7). While RAPT demonstrated the greatest discriminative ability in identifying nonhome discharge (AUC: 0.772), mFI-5 (AUC: 0.720) was also an acceptable predictors of nonhome discharge.
The mFI-5 performs similarly to RAPT in predicting 30-day TJA outcomes. Using the mFI-5 may aid preoperative risk stratification to optimally identify candidates for home discharge.
已创建了诸如风险评估与预测工具(RAPT)和5项改良衰弱指数(mFI-5)等预测工具,以协助全关节置换术(TJA,包括髋和膝关节置换术)后的出院计划制定,但对于衰弱风险尚无统一的判定标准。主要目的是比较改良衰弱指数和RAPT在评估TJA术后结局方面的效果,我们假设这两种方法的表现相似。
我们在一个单一的学术三级中心,对年龄50岁及以上接受初次择期TJA的患者进行了一项回顾性研究,所有患者均遵循相同的术后加速康复方案。根据术前门诊就诊时记录的mFI-5和RAPT评分对患者进行分层。进行多变量分析以评估mFI-5和RAPT与并发症、住院时间延长、再入院和非回家出院之间的独立关联。使用约登指数构建受试者工作特征曲线,以评估mFI-5、Charlson合并症指数和RAPT对结局分类的预测能力。
共纳入858例TJA患者。总体而言,547例(63.8%)无衰弱,273例(31.8%)为衰弱前期,38例(4.4%)为衰弱。按RAPT分层时,369例(43.0%)的RAPT>9(低风险),402例(46.9%)的RAPT为6 - 9(中度风险),87例(10.1%)的RAPT<6(高风险)。衰弱前期(优势比[OR]:2.31,P = .006)和衰弱(OR:8.82,P < .001)与非回家出院的发生率较高相关。RAPT为6 - 9(OR:4.87,P = .001)和RAPT<6(OR:27.2,P < .001)均与非回家出院相关。两者均未与并发症或再入院独立相关。这些指数对并发症、再入院和住院时间延长的独立预测能力较差(所有曲线下面积[AUC]<0.7)。虽然RAPT在识别非回家出院方面表现出最大的判别能力(AUC:0.772),但mFI-5(AUC:0.720)也是非回家出院的可接受预测指标。
mFI-5在预测TJA术后30天结局方面的表现与RAPT相似。使用mFI-5可能有助于术前风险分层,以最佳地识别适合回家出院的患者。