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在创伤登记系统中追踪下肢骨折患者出院后发生感染的情况。

Tracking patients with lower-extremity fracture in a trauma registry who develop an infection after discharge.

作者信息

Oliphant Bryant W, Gerhardinger Laura J, Regenbogen Scott E, Norton Edward C, Scott John W, Winchell Robert J, Miller Anna N, Hemmila Mark R

机构信息

Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI; Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI.

Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI; Department of Surgery, University of Michigan, Ann Arbor, MI.

出版信息

Surgery. 2025 Jun 30;185:109522. doi: 10.1016/j.surg.2025.109522.

Abstract

BACKGROUND

Lower-extremity fracture infections in patients with trauma represent a substantial burden; however, quality improvement initiatives are limited to the acute hospital admission, for a complication that often develops after discharge. We tracked patients with a lower-extremity fracture who developed an infection after discharge from their index trauma center admission and characterized factors associated with this complication using collaborative quality initiative data.

METHODS

Trauma collaborative quality initiative data (1/2018-9/2022) were analyzed from 35 American College of Surgeons Committee on Trauma-verified Level 1 and Level 2 trauma centers and were linked to insurance claims to create a longitudinal patient record. Inpatient and postdischarge lower-extremity fracture infection rates and the location of subsequent follow-up were captured. Multivariable logistic regression assessed the factors associated with developing a postdischarge infection.

RESULTS

There were 11,017 patients with a lower-extremity fracture and 380 (3.4%) developed an infection after discharge, and very few during the index trauma center admission. An open injury increased the probability of an infection by 3.61 percentage points, along with male sex (0.93 percentage points) and multiple medical comorbidities. Almost two-thirds of the infections were diagnosed at a location other than the index trauma center.

CONCLUSION

The overwhelming majority of lower-extremity fracture infections occur after discharge from the index trauma center, and most patients seek care at another location. Known risk factors for developing an infection were confirmed in this large population-based cohort. We successfully linked trauma registry patients with insurance claims to create a longitudinal patient record, which will allow for further studies in this population.

摘要

背景

创伤患者的下肢骨折感染带来了沉重负担;然而,质量改进措施仅限于急性住院期间,而这种并发症往往在出院后才出现。我们追踪了在其初次创伤中心入院出院后发生感染的下肢骨折患者,并使用协作质量改进计划数据对与该并发症相关的因素进行了特征分析。

方法

分析了来自35个经美国外科医师学会创伤委员会验证的一级和二级创伤中心的创伤协作质量改进计划数据(2018年1月至2022年9月),并将其与保险理赔记录相链接以创建患者纵向记录。记录了住院期间和出院后下肢骨折的感染率以及后续随访地点。多变量逻辑回归分析评估了与出院后感染相关的因素。

结果

共有11017例下肢骨折患者,其中380例(3.4%)在出院后发生感染,而在初次创伤中心住院期间感染的患者很少。开放性损伤使感染概率增加3.61个百分点,男性(增加0.93个百分点)和多种内科合并症也有同样影响。几乎三分之二的感染是在初次创伤中心以外的地点被诊断出来的。

结论

绝大多数下肢骨折感染发生在初次创伤中心出院后,且大多数患者在其他地点接受治疗。在这个基于人群的大型队列中证实了已知的感染危险因素。我们成功地将创伤登记患者与保险理赔记录相链接以创建患者纵向记录,这将有助于对该人群进行进一步研究。

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