Fei Dai-Liang, Liu Ying, Liu Jia, Yu Ze, Dong Jin-Liang
Department of General Surgery, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang, China.
Department of Pharmacy, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, China.
Front Microbiol. 2025 Jun 19;16:1554458. doi: 10.3389/fmicb.2025.1554458. eCollection 2025.
The gut microbiota is essential for overall health, and in recent years, there has been increasing interest in its complex relationship with the "gut-liver-kidney axis." In this research, we aim to examine how the gut microbiota affects metabolic and immune responses via influencing the functions of the liver and kidneys. It will also analyze potential pathological mechanisms involved in this interaction and discuss therapeutic strategies that focus on modulating the gut microbiota. Through thoroughly reviewing existing literature, this article intends to offer fresh perspectives and insights that could inform future research and clinical applications in this rapidly developing area of study.
肠道微生物群对整体健康至关重要,近年来,人们对其与“肠-肝-肾轴”的复杂关系越来越感兴趣。在本研究中,我们旨在探讨肠道微生物群如何通过影响肝脏和肾脏的功能来影响代谢和免疫反应。它还将分析这种相互作用中涉及的潜在病理机制,并讨论专注于调节肠道微生物群的治疗策略。通过全面回顾现有文献,本文旨在提供新的观点和见解,为这一快速发展的研究领域的未来研究和临床应用提供参考。