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城市化与儿童哮喘。

Urbanization and childhood asthma.

作者信息

Pham Teresia T, Akinbolagbe Yeside, Nguyen Thinh H, Phipatanakul Wanda

机构信息

Department of Pediatrics, Tufts School of Medicine, Boston, Massachusetts, USA.

Atrius Health, Medford, Massachusetts, USA.

出版信息

Pediatr Allergy Immunol. 2025 Jul;36(7):e70137. doi: 10.1111/pai.70137.

Abstract

Childhood asthma is one of the major public health concerns, and urbanization as well as worsening environmental factors are contributing to its increasing prevalence. Outdoor pollutants, such as PM2.5, ozone, and traffic-related air pollution or TRAP, play significant roles in exacerbating asthmatic symptoms in children as well as reducing their lung function. Climate change can further compound these effects with changing pollen patterns that increase exposure to allergens in certain geographical areas. Moreover, indoor environments in urban areas also expose children to pollutants such as nitrogen dioxide, particulate matter, and aeroallergens like cockroach or mouse allergens. Socioeconomic disparities can further amplify these effects, with children in minority or low-income households disproportionately burdened by asthma morbidity. Green infrastructure and technological innovations can offer mitigation opportunities for negative effects of urbanization but require careful implementation to address multifactorial contributors to childhood asthma. Our review highlights the need for integrated strategies regarding environmental regulation, urban planning, and targeted interventions to reduce asthma burden in the urban pediatric population.

摘要

儿童哮喘是主要的公共卫生问题之一,城市化以及日益恶化的环境因素导致其患病率不断上升。室外污染物,如细颗粒物(PM2.5)、臭氧以及与交通相关的空气污染(TRAP),在加重儿童哮喘症状以及降低其肺功能方面发挥着重要作用。气候变化会随着花粉模式的改变进一步加剧这些影响,从而增加某些地理区域内儿童接触过敏原的机会。此外,城市地区的室内环境也使儿童接触到诸如二氧化氮、颗粒物以及蟑螂或小鼠过敏原等空气过敏原。社会经济差距会进一步放大这些影响,少数族裔或低收入家庭的儿童承受着不成比例的哮喘发病负担。绿色基础设施和技术创新可为城市化的负面影响提供缓解机会,但需要谨慎实施,以应对导致儿童哮喘的多因素成因。我们的综述强调,需要制定关于环境监管、城市规划和针对性干预措施的综合战略,以减轻城市儿童群体的哮喘负担。

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