James Arun Roy, Dhanesh N, Babu Eldho, Devanandan Aswathy, Varghese G Harry, Issac Annie V
Department of Pediatric and Preventive Dentistry, St Gregorios Dental College, Kothamangalam, Ernakulam, Kerala, India.
Department of Periodontics, St Gregorios Dental College, Chelad, Kothamagalam, Kerala, India.
J Pharm Bioallied Sci. 2025 Jun;17(Suppl 2):S1448-S1450. doi: 10.4103/jpbs.jpbs_1880_24. Epub 2025 Jun 18.
Improving the longevity of restorative materials requires efficient cavity cleaning. It is especially crucial to comprehend how various cavity disinfectants affect the binding strength of restorative materials in primary teeth, where caries advancement happens quickly.
This study examined the effects of three cavity disinfectants on the bond strength of restorative materials in primary teeth: 38% silver diamine fluoride (SDF), 5.25% sodium hypochlorite, and 2% chlorhexidine gluconate. Four groups were randomly selected from among 60 removed primary molars with standardized class I cavities: the control group (no disinfectant), the chlorhexidine group, the sodium hypochlorite group, and the SDF group. Composite resin was used to repair cavities after the specified disinfectants were applied. A universal testing equipment was used to assess the bond strength at a crosshead speed of 0.5 mm/min. ANOVA and post-hoc Tukey's tests were used for statistical analysis, with significance set at = 0.05.
The control group had a mean bond strength (MPa) of 12.5 ± 1.8, followed by the chlorhexidine group (15.3 ± 2.0), the sodium hypochlorite group (14.1 ± 1.7), and the SDF group (9.8 ± 1.5). SDF had the lowest bond strength ( < 0.01), whereas chlorhexidine had the strongest, far outperforming the control group ( < 0.01). Additionally, sodium hypochlorite showed a significant improvement over the control group ( < 0.05).
When compared to sodium hypochlorite and SDF, chlorhexidine gluconate significantly increased the binding strength of restorative materials in primary teeth. Despite the decreased binding strength, SDF's antibacterial qualities point to possible therapeutic uses that merit more research. When choosing a cavity disinfectant, one should carefully consider both the product's antibacterial properties and its impact on bond strength.
提高修复材料的使用寿命需要有效的窝洞清洁。了解各种窝洞消毒剂如何影响乳牙修复材料的粘结强度尤为重要,因为乳牙龋病进展迅速。
本研究考察了三种窝洞消毒剂对乳牙修复材料粘结强度的影响:38%氟化亚银(SDF)、5.25%次氯酸钠和2%葡萄糖酸氯己定。从60颗拔除的具有标准化Ⅰ类洞的乳磨牙中随机选取四组:对照组(不使用消毒剂)、氯己定组、次氯酸钠组和SDF组。在使用指定的消毒剂后,用复合树脂修复窝洞。使用万能测试设备以0.5mm/min的十字头速度评估粘结强度。采用方差分析和事后Tukey检验进行统计分析,显著性设定为α = 0.05。
对照组的平均粘结强度(MPa)为12.5±1.8,其次是氯己定组(15.3±2.0)、次氯酸钠组(14.1±1.7)和SDF组(9.8±1.5)。SDF的粘结强度最低(P<0.01),而氯己定的粘结强度最强,远优于对照组(P<0.01)。此外,次氯酸钠组与对照组相比有显著改善(P<0.05)。
与次氯酸钠和SDF相比,葡萄糖酸氯己定显著提高了乳牙修复材料的粘结强度。尽管粘结强度有所下降,但SDF的抗菌特性表明其可能具有值得进一步研究的治疗用途。在选择窝洞消毒剂时,应仔细考虑产品的抗菌性能及其对粘结强度的影响。