Lacanilao Jonathan Paul, de Toledo Clara Alvarez, Padilla Ma Dominga, De la Paz María Fideliz
Anterior Segment Section, St. Luke´s Medical Center, Global City, Philippines.
Anterior Segment Section, OFTALVIST, Barcelona, Spain.
Semin Ophthalmol. 2025 Jul 15:1-5. doi: 10.1080/08820538.2025.2530550.
To describe the use of oral mucosa overlay in Boston Keratoprosthesis surgery as an adjunct in complex cases.
Retrospective case series on eyes that underwent Type I Boston keratoprosthesis where oral mucosa was used as an adjunct procedure.
30 eyes were identified. The oral mucosa may be used as a salvaging technique for an extruded Type I Boston Keratoprosthesis. In cases of severe dry eye where osteo-odontokeratoprosthesis cannot be performed for reasons like edentulia, or patient refusal due to cosmetic reasons, the Boston Keratoprosthesis with mucosa overlay may be performed as a simpler technique. It may also be used as a primary procedure in cases where there is high risk of melt or extrusion for a Type I Boston Keratoprosthesis such as autoimmune corneal opacity, severe chemical burn, congenital aniridia. Surgery can be performed either as a single stage or in two stages, three months apart, to ensure the development of a well-vascularized pedicle flap. Lastly, the mucosa may be used as an alternative covering to a Type II Boston Keratoprosthesis allowing for better cosmesis and easier access for possible future retina or glaucoma surgery.
The use of oral mucosa is widely accessible to corneal surgeons due to the ease of harvesting oral mucosa, and the availability of the Type I Boston KPro. The learning curve is less steeper than the modified osteo-odontokeratoprosthesis and the cosmesis is more acceptable.
描述在复杂病例中,口腔黏膜覆盖物在波士顿人工角膜手术中的应用。
对接受I型波士顿人工角膜手术且使用口腔黏膜作为辅助手术的眼睛进行回顾性病例系列研究。
共纳入30只眼睛。口腔黏膜可作为挽救I型波士顿人工角膜脱出的技术。在严重干眼病例中,若因无牙等原因无法进行骨-牙-角膜移植术,或因美容原因患者拒绝手术时,可采用带黏膜覆盖的波士顿人工角膜手术,该手术更为简单。在I型波士顿人工角膜有较高融化或脱出风险的病例中,如自身免疫性角膜混浊、严重化学烧伤、先天性无虹膜,也可将其作为主要手术方式。手术可一期完成,也可分两期进行,间隔三个月,以确保形成血管化良好的带蒂皮瓣。最后,黏膜可作为II型波士顿人工角膜的替代覆盖物,具有更好的美容效果,且便于未来可能进行的视网膜或青光眼手术。
由于获取口腔黏膜容易,且有I型波士顿人工角膜,角膜外科医生广泛采用口腔黏膜覆盖技术。其学习曲线比改良骨-牙-角膜移植术更平缓,美容效果更易接受。