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Progression Independent of the Triggering Event in Neurologic Diseases.

作者信息

Weiner Howard L

机构信息

Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

出版信息

Neurol Neuroimmunol Neuroinflamm. 2025 Sep;12(5):e200447. doi: 10.1212/NXI.0000000000200447. Epub 2025 Jul 16.

DOI:10.1212/NXI.0000000000200447
PMID:40669038
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12270492/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e511/12270492/985093787afe/NXI-2025-200318f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e511/12270492/985093787afe/NXI-2025-200318f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e511/12270492/985093787afe/NXI-2025-200318f1.jpg

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N Engl J Med. 2025 May 15;392(19):1883-1892. doi: 10.1056/NEJMoa2415988. Epub 2025 Apr 8.
2
Immune mechanisms and shared immune targets in neurodegenerative diseases.神经退行性疾病中的免疫机制和共同免疫靶点
Nat Rev Neurol. 2025 Feb;21(2):67-85. doi: 10.1038/s41582-024-01046-7. Epub 2024 Dec 16.
3
Determinants and Biomarkers of Progression Independent of Relapses in Multiple Sclerosis.多发性硬化症中与复发无关的进展的决定因素和生物标志物。
Ann Neurol. 2024 Jul;96(1):1-20. doi: 10.1002/ana.26913. Epub 2024 Apr 3.
4
Disease-associated astrocyte epigenetic memory promotes CNS pathology.疾病相关星形胶质细胞表观遗传记忆促进中枢神经系统病理学。
Nature. 2024 Mar;627(8005):865-872. doi: 10.1038/s41586-024-07187-5. Epub 2024 Mar 20.
5
Head trauma results in manyfold increased risk of multiple sclerosis in genetically susceptible individuals.头部创伤导致遗传易感个体多发性硬化症的风险增加多倍。
J Neurol Neurosurg Psychiatry. 2024 May 14;95(6):554-560. doi: 10.1136/jnnp-2023-332643.
6
Neuroinflammation: An astrocyte perspective.神经炎症：星形胶质细胞的观点。
Sci Transl Med. 2023 Nov 8;15(721):eadi7828. doi: 10.1126/scitranslmed.adi7828.
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Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial.多奈哌齐治疗早期症状性阿尔茨海默病的随机临床试验。
JAMA. 2023 Aug 8;330(6):512-527. doi: 10.1001/jama.2023.13239.
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Multiple sclerosis: Neuroimmune crosstalk and therapeutic targeting.多发性硬化症：神经免疫相互作用和治疗靶点。
Cell. 2023 Mar 30;186(7):1309-1327. doi: 10.1016/j.cell.2023.03.008.
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Lecanemab in Early Alzheimer's Disease.早期阿尔茨海默病中的lecanemab
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