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维生素A及其相关疾病。

Vitamin A and Its Related Diseases.

作者信息

Rao Shuhan, Li Tiewei, Li Xiaojuan, Hou Ligong, Sun Wan

机构信息

Department of Clinical Laboratory, Zhengzhou Key Laboratory of Children's Infection and Immunity Children's Hospital Affiliated to Zhengzhou University Zhengzhou China.

Henan International Joint Laboratory of Prevention and Treatment of Pediatric Diseases Children's Hospital Affiliated to Zhengzhou University Zhengzhou China.

出版信息

Food Sci Nutr. 2025 Jul 15;13(7):e70630. doi: 10.1002/fsn3.70630. eCollection 2025 Jul.

Abstract

Vitamin A (VA), an essential micronutrient, plays a pivotal role in human growth, development, immune function, and vision. Vitamin A deficiency not only affects children's vision and growth, but also increases their susceptibility to infectious diseases, such as respiratory and gastrointestinal infections. Deficiency in vitamin A not only disrupts growth and development in children but also increases susceptibility to infectious diseases, such as respiratory and gastrointestinal infections. From an immunological standpoint, vitamin A is essential for the proper development and function of the immune system, with its deficiency impairing immune responses. Emerging evidence also suggests a role for vitamin A in the pathogenesis of systemic diseases, including metabolic and autoimmune disorders. Therefore, monitoring and managing vitamin A levels are of great significance in disease prevention and treatment. To fully understand the mechanism of vitamin A in various clinical diseases, it is important to provide a theoretical basis for improving the nutritional status of vitamin A to reduce the incidence of diseases and improve patient outcomes.

摘要

维生素A(VA)是一种必需的微量营养素,在人类生长、发育、免疫功能和视力方面发挥着关键作用。维生素A缺乏不仅会影响儿童的视力和生长,还会增加他们对传染病的易感性,如呼吸道和胃肠道感染。维生素A缺乏不仅会扰乱儿童的生长发育,还会增加他们对传染病的易感性,如呼吸道和胃肠道感染。从免疫学角度来看,维生素A对免疫系统的正常发育和功能至关重要,其缺乏会损害免疫反应。新出现的证据还表明维生素A在包括代谢和自身免疫性疾病在内的全身性疾病的发病机制中发挥作用。因此,监测和管理维生素A水平在疾病预防和治疗中具有重要意义。为了充分了解维生素A在各种临床疾病中的作用机制,为改善维生素A营养状况以降低疾病发生率和改善患者预后提供理论依据很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f9d/12263517/bbbd311edb4d/FSN3-13-e70630-g002.jpg

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