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辣木树的营养成分及肾脏保护潜力()。 (注:原文括号处内容缺失,翻译按现有内容完整呈现)

Nutritional content and renoprotective potential of miracle tree ().

作者信息

Sharma Vibhuti, Mahajan Gaytri, Gupta Reena

机构信息

Department of Biotechnology, Himachal Pradesh University, Summerhill, Shimla, India.

出版信息

BioTechnologia (Pozn). 2025 Jun 30;106(2):223-239. doi: 10.5114/bta/204529. eCollection 2025.

Abstract

Kidney disease is a significant global health issue. This review explores the causes of renal illness, the therapeutic properties of the angiosperm , and its potential effectiveness in kidney disease management. In chronic kidney disease, inflammatory processes and immune cell activation lead to excessive free radical production, resulting in oxidative stress due to diminished antioxidant capacity. possesses diverse health benefits, particularly its ability to enhance antioxidant defenses. Extracts from its stem, seed, and leaf powders have been shown to increase the activity of key antioxidant enzymes, including glutathione, superoxide dismutase, and catalase. Additionally, modulates inflammation by reducing the activity of TNF-α, COX-2, and other pro-inflammatory cytokines. This review provides insights into the pharmacological and therapeutic potential of , highlighting its promise in the development of novel treatments for kidney-related disorders. Moreover, its bioactive compounds may contribute to renal tissue regeneration and protection against nephrotoxic agents.

摘要

肾脏疾病是一个重大的全球健康问题。本综述探讨了肾脏疾病的病因、被子植物的治疗特性及其在肾脏疾病管理中的潜在有效性。在慢性肾脏疾病中,炎症过程和免疫细胞激活导致自由基过度产生,由于抗氧化能力下降而导致氧化应激。[被子植物名称]具有多种健康益处,特别是其增强抗氧化防御的能力。其茎、种子和叶粉提取物已被证明可增加关键抗氧化酶的活性,包括谷胱甘肽、超氧化物歧化酶和过氧化氢酶。此外,[被子植物名称]通过降低肿瘤坏死因子-α、环氧化酶-2和其他促炎细胞因子的活性来调节炎症。本综述深入探讨了[被子植物名称]的药理和治疗潜力,突出了其在开发肾脏相关疾病新疗法方面的前景。此外,其生物活性化合物可能有助于肾脏组织再生和对抗肾毒性药物的保护作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8efc/12281497/fbcd51aa9605/BTA-106-2-204529-g001.jpg

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