加沙地带政府医院心脏监护病房收治患者急性冠状动脉综合征的危险因素：病例对照研究
Risk factors of acute coronary syndrome among patients admitted to cardiac care units at governmental hospitals in the Gaza Strip: Case- control study.
作者信息
Khattab Tareq, Aljeesh Yousef
机构信息
Clinical Nurse Instructor, University College of Applied Sciences - Palestine, Gaza, Palestine.
Al-Aqsa Martyrs Hospital, Dair Al-Balah, Gaza, Palestine.
出版信息
Int J Cardiol Cardiovasc Risk Prev. 2025 Jul 12;26:200466. doi: 10.1016/j.ijcrp.2025.200466. eCollection 2025 Sep.
BACKGROUND
Acute coronary syndrome represents a major global health issue. The aim of the study was to identify the risk factors related to acute coronary syndrome among patients admitted to cardiac care units in governmental hospitals in the Gaza Strip.
METHODS
An analytical case-control study was conducted from February to September 2023, involving 300 participants (100 cases and 200 controls) selected by quota sampling from governmental hospitals in the Gaza Strip. The data were collected using structured interviews and questionnaires. Reliability testing by Cronbach's alpha coefficient (0.87) and statistical analysis was conducted using SPSS version 25.
RESULT
Among the participants, 78 % were male while 22 % were female. 30 % fell into the age group of 56-60 years, and 34 % received treatment at Al Shifa Medical Complex. The logistic regression analysis revealed several significant risk factors associated with acute coronary syndrome. These included lower income (OR = 2.32, 95 % CI: 1.36-3.94, p = 0.002) and family history of acute coronary syndrome (OR = 5.46, 95 % CI: 3.24-9.19, p < 0.001). smoking (OR = 4.38, 95 % CI: 2.62-7.34, p < 0.001). A history of hypertension, diabetes mellitus, dyslipidemia, atrial fibrillation, and NSAID drug use is associated with acute coronary syndrome, overweight (OR = 2.86, 95 % CI: 1.58-5.19, p = 0.001), obesity (OR = 6.74, 95 % CI: 3.30-13.78, p < 0.001), higher waist-to-height ratio (OR = 3.75, 95 % CI: 1.62-8.66, p = 0.002), and waist-to-hip ratio (OR = 5.07, 95 % CI: 2.64-9.71, p < 0.001).
CONCLUSION
This study highlights lower income and familial predisposition as critical acute coronary syndrome predictors in Gaza, alongside traditional risks like obesity and smoking. Implementing strategies to control these risk factors and improve preventive measures is crucial for reducing the incidence of acute coronary syndrome.
背景
急性冠状动脉综合征是一个重大的全球健康问题。本研究的目的是确定加沙地带政府医院心脏监护病房收治患者中与急性冠状动脉综合征相关的危险因素。
方法
2023年2月至9月进行了一项分析性病例对照研究，涉及300名参与者（100例病例和200名对照），通过配额抽样从加沙地带的政府医院选取。数据通过结构化访谈和问卷收集。采用Cronbach'sα系数进行信度测试（0.87），并使用SPSS 25版进行统计分析。
结果
参与者中，78%为男性，22%为女性。30%属于56 - 60岁年龄组，34%在希法医疗中心接受治疗。逻辑回归分析显示了几个与急性冠状动脉综合征相关的重要危险因素。这些因素包括低收入（比值比=2.32，95%置信区间：1.36 - 3.94，p = 0.002）、急性冠状动脉综合征家族史（比值比=5.46，95%置信区间：3.24 - 9.19，p < 0.001）、吸烟（比值比=4.38，95%置信区间：2.62 - 7.34，p < 0.001）。高血压、糖尿病、血脂异常、心房颤动和使用非甾体抗炎药的病史与急性冠状动脉综合征相关，超重（比值比=2.86，95%置信区间：1.58 - 5.19，p = 0.001）、肥胖（比值比=6.74，95%置信区间：3.30 - 13.78，p < 0.001）、较高的腰高比（比值比=3.75，95%置信区间：1.62 - 8.66，p = 0.002）和腰臀比（比值比=5.07，95%置信区间：2.64 - 9.71，p < 0.001）。
结论
本研究强调低收入和家族易感性是加沙急性冠状动脉综合征的关键预测因素，同时还有肥胖和吸烟等传统风险因素。实施控制这些危险因素的策略并改进预防措施对于降低急性冠状动脉综合征的发病率至关重要。
Zotero 插件