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一例重症中风后复发性吸入性肺炎和高渗高血糖状态及其经放射介入胃造口术(RIG)置管治疗

A Case of Recurrent Aspiration Pneumonia and Hyperosmolar Hyperglycemic State Following Severe Stroke and Its Management With Radiologically Inserted Gastrostomy (RIG) Tube Placement.

作者信息

Asif Zain

机构信息

Stroke Medicine, Fairfield General Hospital, Bury, GBR.

出版信息

Cureus. 2025 Jun 27;17(6):e86846. doi: 10.7759/cureus.86846. eCollection 2025 Jun.

Abstract

This report describes the case of a 65-year-old previously healthy man who presented with a severe left pontine ischaemic stroke, resulting in significant neurological deficits and a prolonged hospital stay. He had a pre-morbid modified Rankin Score of 0, with a background of type 2 diabetes mellitus (HbA1c 86 mmol/mol), a history of smoking, recurrent vomiting, and oesophagitis. During admission, he developed frequent episodes of aspiration pneumonia, which significantly complicated his recovery. His Glasgow Coma Scale (GCS) remained low (E4M6V1) throughout, indicating limited neurological improvement. Posterior circulation strokes involving the pons are particularly severe due to the concentration of cranial nerve nuclei and vital autonomic pathways in this region. His clinical course was further complicated by the development of a hyperosmolar hyperglycaemic state (HHS), requiring medical management. As his condition progressed, peripheral venous access became increasingly difficult, eventually necessitating central venous catheter insertion. Following the placement of a radiologically-inserted gastrostomy (RIG) tube, the frequency of aspiration-related chest infections reduced, and his condition temporarily stabilised. However, his overall neurological and functional recovery remained limited. He was eventually discharged to a nursing home but sadly passed away several months later due to ongoing complications. This case highlights the challenges in managing patients with severe brainstem strokes complicated by recurrent aspiration pneumonia, metabolic disturbances such as HHS, and vascular access difficulties. It also reflects the potential role of RIG feeding in reducing respiratory complications in patients with severe dysphagia.

摘要

本报告描述了一名65岁既往健康男性的病例,该患者出现严重的左侧脑桥缺血性卒中,导致显著的神经功能缺损和住院时间延长。他病前改良Rankin量表评分为0,有2型糖尿病(糖化血红蛋白86 mmol/mol)、吸烟史、反复呕吐和食管炎病史。住院期间,他频繁发生吸入性肺炎,这显著影响了他的康复。他的格拉斯哥昏迷量表(GCS)始终较低(E4M6V1),表明神经功能改善有限。由于该区域集中了颅神经核和重要的自主神经通路,累及脑桥的后循环卒中尤为严重。他的临床病程因高渗高血糖状态(HHS)的出现而进一步复杂化,需要进行医学处理。随着病情进展,外周静脉通路越来越难以建立,最终需要插入中心静脉导管。在放置了经放射学插入的胃造口术(RIG)管后,与吸入相关的肺部感染频率降低,他的病情暂时稳定。然而,他的整体神经和功能恢复仍然有限。他最终出院至养老院,但遗憾的是,几个月后因持续的并发症去世。该病例突出了管理患有严重脑干卒中并伴有反复吸入性肺炎、HHS等代谢紊乱以及血管通路困难的患者所面临的挑战。它还反映了RIG喂养在减少严重吞咽困难患者呼吸并发症方面的潜在作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6e3/12296948/e17f270fa5b6/cureus-0017-00000086846-i01.jpg

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