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慢性肾功能不全患者中罕见的结核性腹膜炎发病情况

Rare Onset of Tubercular Peritonitis Amidst Chronic Renal Dysfunction.

作者信息

Popa Romeo, Georgescu Cristian-Corneliu, Caragea Daniel-Cosmin, Cana-Ruiu Daniela, Ene Cristina, Radu Lucretiu, Gheorman Victor, Varut Marius-Ciprian, Gheorman Veronica, Orezanu Andrei, Codea Andrei Razvan, Ghilusi Mirela, Popa Loredana-Adriana, Diaconu Magdalena

机构信息

Department of Pharmacology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.

Department of Nephrology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.

出版信息

Reports (MDPI). 2023 Sep 22;6(4):44. doi: 10.3390/reports6040044.

DOI:10.3390/reports6040044
PMID:40729167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12225301/
Abstract

Tuberculosis Peritonitis is a serious condition, whose diagnosis is established late due to the nonspecific nature of the clinical features, which delays the performance of imaging investigations and, implicitly, the setting of the diagnosis through biopsy and histopathological examination. We report the case of a 49-year-old man who presented in our clinic with nonspecific symptoms and significant nitrogen retention, with ascites fluid detected during the clinical-paraclinical examination, ultimately confirming the diagnosis of bacillary peritonitis. Confirmation of tuberculous etiology through biopsy and/or bacteriological examination is sovereign for the diagnosis. The therapeutic protocol includes three anti-tuberculostatic drugs, for a period of at least 6 months, with or without the combination of corticosteroid therapy during the first months of treatment. The patient evolution under treatment was initially favorable, but due to peritoneal adhesions, it underwent complications later.

摘要

结核性腹膜炎是一种严重疾病,因其临床特征不具特异性,诊断往往延迟,这导致影像学检查滞后,进而也延误了通过活检和组织病理学检查来确诊。我们报告一例49岁男性病例,该患者因非特异性症状和显著氮潴留前来我院就诊,临床辅助检查时发现腹水,最终确诊为细菌性腹膜炎。通过活检和/或细菌学检查确认结核病因对诊断至关重要。治疗方案包括三种抗结核药物,疗程至少6个月,治疗最初几个月可联合或不联合皮质类固醇治疗。患者治疗初期病情进展良好,但后来因腹膜粘连出现了并发症。

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本文引用的文献

1
Abdominal Tuberculosis in Children: A Case Series of Five Patients.儿童腹部结核病:五例病例系列
Microorganisms. 2023 Mar 12;11(3):730. doi: 10.3390/microorganisms11030730.
2
A Current Perspective on the Potential of Nanomedicine for Anti-Tuberculosis Therapy.纳米医学在抗结核治疗中的潜力现状展望
Trop Med Infect Dis. 2023 Feb 3;8(2):100. doi: 10.3390/tropicalmed8020100.
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Small Bowel Obstruction As a Consequence of Peritoneal Tuberculosis.腹膜结核导致的小肠梗阻
Bull Emerg Trauma. 2022;10(4):196-200. doi: 10.30476/BEAT.2021.91273.1277.
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The Use of Mesenchymal Stem Cells in the Complex Treatment of Kidney Tuberculosis (Experimental Study).间充质干细胞在肾结核综合治疗中的应用(实验研究)
Biomedicines. 2022 Nov 28;10(12):3062. doi: 10.3390/biomedicines10123062.
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Review and Updates on the Diagnosis of Tuberculosis.结核病诊断的回顾与更新
J Clin Med. 2022 Sep 30;11(19):5826. doi: 10.3390/jcm11195826.
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Diagnostic performance of adenosine deaminase for abdominal tuberculosis: A systematic review and meta-analysis.腺苷脱氨酶对腹腔结核的诊断性能:系统评价和荟萃分析。
Front Public Health. 2022 Sep 21;10:938544. doi: 10.3389/fpubh.2022.938544. eCollection 2022.
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Tuberculosis incidence in patients with chronic kidney disease: a systematic review and meta-analysis.慢性肾脏病患者结核病发病率:系统评价和荟萃分析。
Int J Infect Dis. 2022 Sep;122:188-201. doi: 10.1016/j.ijid.2022.05.046. Epub 2022 May 21.
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Diagnosis of Peritoneal Tuberculosis from Primary Peritoneal Cancer.原发性腹膜癌与结核性腹膜炎的鉴别诊断。
Int J Environ Res Public Health. 2021 Oct 3;18(19):10407. doi: 10.3390/ijerph181910407.
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New Antibiotics for Multidrug-Resistant Bacterial Strains: Latest Research Developments and Future Perspectives.多药耐药菌新抗生素:最新研究进展及未来展望。
Molecules. 2021 May 2;26(9):2671. doi: 10.3390/molecules26092671.
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Peritoneal tuberculosis mimicking carcinomatous ascites in a child living in a low prevalence country: a case report.低发国家儿童腹膜结核酷似癌性腹水:1 例病例报告。
Ital J Pediatr. 2020 Apr 19;46(1):49. doi: 10.1186/s13052-020-0816-6.